Current estimated net worth: $45 million
Former North Carolina Sen. John Edwards sought the Democratic presidential nominations in 2004 and in 2008. The closest he came was in 2004, when he became the running mate for Sen. John Kerry of Massachusetts.
Their ticket was defeated by then-incumbent President George W. Bush and Vice President Dick Cheney, but Edwards returned to the campaign trail four years later, albeit unsuccessfully. He currently has an estimated net worth of $45 million, much of which comes from hedge-fund investments and from awards he won for clients in personal injury and medical malpractice lawsuits.