The analytics company Nitogram released data on responses to that ad, and the results were positive. According to Nitogram, the ad's engagement was successful, increasing followers and total reach.
At the Gigaom Roadmap conference earlier this month, Instagram CEO Kevin Systrom said that more than 5 percent of the ads featured on the platform have garnered "likes."
The Michael Kors ad, posted about three weeks ago, got 229,000-plus "likes" and more than 1,700 comments. There was significant backlash in the comments section about the ad's showing up in the feed of users who aren't brand followers, however.
Bottom line: More "likes" is good for brands. And engagement appears to be up, but as with the Lexus ad, that isn't always positive.
—By CNBC's Cadie Thompson. Follow her on Twitter @CadieThompson.