Twitter's net loss grew by more than $100 million in the first quarter, though the company's operating earnings and revenue beat Wall Street estimates.
Shares fell 9 percent in after-hours trading.
The company broke even, excluding items, and reported revenue of $250 million.
Analysts had expected the company to report a loss, excluding items, of 3 cents a share on $241 million in revenue, according to a consensus estimate from Thomson Reuters.
The net loss grew to $132.4 million, or 23 cents per share, from $27 million or 21 cents per share a year earlier.
Monthly active users hit 255 million, with mobile MAUs making up 78% of the total.
The revenue and earnings were fine but "the audience metric wasn't as good as you'd hoped for," said Tom Forte of the Telsey Advisory Group in an interview on CNBC's Closing Bell.
For the current quarter Twitter forecast revenue of $270 million to $280 million and adjusted operating earnings of $25 million to $30 million. Analysts on average expected revenue of $272.9 million and adjusted operating earnings of $28.8 million.
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