In that role, she worked for Philadelphia Fed President Charles Plosser, who is known for his hawkish views on inflation, calling repeatedly for the Fed to put a faster end to its accommodative monetary policy.
Mester's own monetary policy views are less clear, though her research work and former colleagues indicate she does not necessarily share the stance of her former boss.
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Mester did not reveal much of her interest rate view on Thursday, saying only that the Fed will "eventually" be able to move away from its accommodative tools. She said she expects the central bank's bond buying to end in the fall, echoing Fed statements that say it will wrap up in October.
"Yet, even with the end of the purchase program, the Fed's balance sheet will remain very large, with assets of much longer maturity than usual, and this will complicate the normalization journey," she said.
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The Fed's balance sheet has ballooned from around $1 trillion before the 2008 financial crisis to the current level of around $4.5 trillion.
Mester, who has spent 28 years at the Fed, said that she expects inflation to return to 2 percent over the next two years. In addition, Mester said that the Fed should expect wages to rise with prices, not before.
"It would not be prudent for policymakers to simply wait for wages to accelerate before assessing the implications of the stance of monetary policy for future price inflation," Mester said, imploring policymakers to be forward looking.