Pfizer's $11 billion buyback plan deflates AstraZeneca bid hopes

U.S. drugmaker Pfizer is to continue buying back stock, with the board authorizing a new $11 billion share repurchase plan, deflating expectations that it will make a new bid for AstraZeneca.

Shares in AstraZeneca fell 1.2 percent on Friday following the news. (Get the latest quote here.)

Read MoreLightning Round: Booyah to Pfizer!

The largest American pharmaceuticals company, whose shares gained more than 1 percent after the announcement late on Thursday, said the move was in addition to the $1.3 billion remaining on its current share buyback program.

Viagra made by Pfizer and Nexium made by AstraZeneca.
Getty Images
Viagra made by Pfizer and Nexium made by AstraZeneca.

Pfizer, which has a market valuation of about $180 billion, earlier this year failed in its $118 billion bid to buy British rival AstraZeneca. It has an opportunity to make a fresh run at its target from late November under British takeover rules.

Pfizer Chief Executive Ian Read has said the company is continuing to look at deals but investor hopes for a new bid have dwindled recently because of the introduction of new U.S. tax rules.

Read MoreDad-turned-CEO inks Pfizer deal for Duchenne drugs

The U.S. government's tax proposals are designed to make it harder for American firms to shift their tax bases out of the country and into lower cost jurisdictions in Europe, as Pfizer would do by buying AstraZeneca.

The likelihood of Pfizer resuming its pursuit has also been diminished following the collapse of U.S. drugmaker AbbVie's $55 billion plan to buy Dublin-based Shire, as a result of the new U.S. tax regulations.

But while investors may well view the big new share buyback as another blow to the idea of a Pfizer bid, ISI Group analyst Mark Schoenebaum cautioned against reading too much into it. "We cannot and should not necessarily make that read-across," he said in a note.

Pfizer eyed Actavis takeover: Report
Pfizer eyed Actavis takeover: Report