Regions Financial on Tuesday reported fourth-quarter profit dropped by almost 4 percent to $211 million.
The bank, based in Birmingham, Alabama, said it had earnings of 14 cents per share.
The results missed Wall Street expectations. The average estimate of analysts surveyed by Zacks Investment Research was for earnings of 21 cents per share.
The holding company for Regions Bank posted revenue of $1.27 billion in the period, also missing Street forecasts. Analysts expected $1.3 billion, according to Zacks.
For the year, the company said profit rose 6 percent to $1.16 billion, or 80 cents per share. Revenue fell 10 percent to $5.1 billion.
Regions Financial shares have declined 14 percent since the beginning of the year, while the Standard & Poor's 500 index has declined almost 2 percent. The stock has fallen 14 percent in the last 12 months.