Due in large part to the sky-high valuations of Silicon Valley's technology darlings, San Francisco's start-up scene has been a dominant story line in recent years — and rightfully so. But a powerful ecosystem has emerged in San Diego for entrepreneurs, bolstered by the fact it has developed itself as a center of excellence in biotech and life sciences, mobile technology and aerospace research.
According to data from the Kauffman Foundation's "Startup Activity" report, San Diego ranks as a top 10 start-up city for the past two years, advancing one spot to No. 9 in 2015. Eighty percent of entrepreneurs are considered "opportunity share" in the metro, meaning founders were not previously unemployed before launching, but instead started up as they saw an opportunity in the market. What's more, there are nearly 155 start-ups for every 100,000 residents in the area.