Judge Amy Berman Jackson is presiding over the Anthem-Cigna bench trial and has promised to issues a ruling in the case in January, but the case is unfolding against the backdrop of a major shift in Washington when it comes to health care.
President-elect Donald J. Trump and the incoming Republican-controlled Congress have vowed to repeal and replace Obamacare, President Barack Obama's signature health reform law.
Inside the courtroom, the fate of the Affordable Care Act may not matter in this case, said Goodwin's Andrea Murino.
"What judge Berman Jackson will do is just look at the world as it is today, because that's all she really can do," Murino said, "We don't know what a Trump presidency will look like. We don't know what's going to happen… with the ACA or the (health insurance) exchanges. We just can't predict that."
Some analysts and investors have anticipated that the Trump administration will be more merger-friendly and less aggressive than the Obama administration in pursuing antitrust cases.
Professor Tim Greaney said any deal of the size of the Anthem-Cigna and Aetna-Humana health insurance mergers would invite scrutiny under any administration.
"Historically, antitrust has been a fairly bipartisan affair. There has a been a consensus in the United States that competition is good and it's harmed when monopolies get created," Greaney said.
Follow CNBC International on Twitter and Facebook.