CNBC used government and private data to analyze and find the best metro areas to launch a business based on 20 key criteria.
Many start-ups receive tons of funding for taking control of an untapped market. But that doesn't mean they have great patent protection.
Uber now has a $66 billion valuation and is No. 1 on the 2016 CNBC Disruptor 50 list, but the car giant still faces a major challenge.
CNBC reveals the methodology for the 2016 Disruptor 50 list, the start-ups thinking big about monumental consumer and business shifts.