European equities were in negative territory as oil prices, Greek elections managed to dent investor sentiment.
Gold continues drop after the Fed's bullish picture of the U.S. economy, signalling it was on course to lift interest rates this year.
NZ dollar slumped to four-year lows with the risk of rate cuts, while the dollar looks up on the Fed's latest policy statement.
Oil remained weak after data showed record U.S. stockpile and analysts said a global glut would continue to keep the market under pressure.
Asian indices were broadly lower early Thursday, as a rout in energy stocks and a slew of disappointing corporate earnings weigh on regional markets.
Stocks declined on Wednesday, a day after the S&P 500 took its biggest hit in more than three weeks.
U.S. government debt prices rallied on Wednesday, amid speculation about the tone of the Fed's latest policy statement, due later Wednesday.
European markets ended mixed on Wednesday after seesawing for much of the session, with indexes pressures by a staggering slump in Greek bank stocks.
Gold hovered in a tight range near $1,290 an ounce on Wednesday as the focus turned to the U.S. Federal Reserve.
The latest increase added to the previous week's build of over 10 million barrels, which was the biggest in 14 years.
The dollar rose against a basket of currencies on Wednesday, recouping some of the previous day's sharp losses.
Asian stocks outside of Shanghai erased losses to end higher on Wednesday, but the mood was cautious ahead of the Federal Reserve's policy decision.
Stocks dropped sharply on Tuesday, as earnings disappointed as did durable-goods data.
U.S. government debt prices strengthened on Monday, pushing yields lower, ahead of the Federal Reserve's closely-watched policy meeting.
US stock index futures signaled a slightly higher open, with European stocks boosted early in the day after Apple smashed analyst expectations.
European markets closed down on Tuesday, after a number of Wall Street's biggest firms missed earnings expectations.
Gold struggled on Tuesday to recover losses from the previous two sessions as a firm U.S. dollar and strength in equities dulled the metal's appeal.
Oil rose more than 3 percent on Tuesday as a weaker dollar propped up commodities priced in the currency.
The euro rose against the dollar before a meeting of the U.S. Federal Reserve that may push back expectations for an interest rate rise.
Asian shares hit fresh highs on Tuesday, as investors deemed a Greek exit from the euro zone unlikely.
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