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  • Isis trading halts as FDA reviews key drug's risks Thursday, 18 Oct 2012 | 12:58 AM ET

    Drug developer Isis Pharmaceuticals Inc. and partner Genzyme said Thursday a panel of advisers to the Food and Drug Administration had voted 9 to 6 to recommend approval of Kynamro, for treating patients genetically predisposed to have sky-high LDL, or bad cholesterol. The FDA is not bound to follow recommendations of its advisers, but usually does so.

  • GM wins dismissal of lawsuit over Einstein image Thursday, 18 Oct 2012 | 12:43 AM ET

    DETROIT-- A federal judge in California has dismissed a lawsuit challenging the use of Albert Einstein's image in a magazine ad by General Motors. The Detroit News says the Hebrew University of Jerusalem filed the lawsuit against GM. Information from: The Detroit News, http://detnews.com/.

  • BioTime makes offer for Geron stem cell assets Thursday, 18 Oct 2012 | 12:36 AM ET

    In a letter to Geron shareholders, BioTime suggests two deals that would form a new publicly traded company owning Geron's stem cell assets with some of BioTime's. It said Geron could have a stake of up to 45 percent in the company, which would also hold $40 million in BioTime stock along with shares of some BioTime stem cell subsidiaries.

  • Dollar rises after mixed US economic data Thursday, 18 Oct 2012 | 12:15 AM ET

    That's a sign layoffs are increasing, but the Labor Department said that there were technical reasons behind rise, such as delayed figures from California. The Federal Reserve Bank of Philadelphia says that manufacturing in the Philadelphia region expanded in October after five months of declines.

  • Shocking! Famed fashion house Schiaparelli revived Thursday, 18 Oct 2012 | 12:08 AM ET

    PARIS-- Shoe hats, lobster dresses, and spiraling goggle glasses could easily be part of a closet inventory belonging to Lady Gaga. The house of the influential fashion designer, and hated rival of Coco Chanel, is being revived this fall, in one of the most highly anticipated fashion events of 2012 in Paris.

  • Average debt up again for new college grads Thursday, 18 Oct 2012 | 12:02 AM ET

    It's the latest snapshot of the growing burden of student debt and it's another discouraging one: Two-thirds of the national college class of 2011 finished school with loan debt, and those who borrowed walked off the graduation stage owing on average $26,600 _ up about 5 percent from the class before.

  • Judge sides with DC Comics in fight over Superman Wednesday, 17 Oct 2012 | 8:48 PM ET

    The ruling means that DC Comics and its owner Warner Bros. will retain all rights to continue using the character in books, films, television and other mediums, including a the film reboot planned for next year.

  • Align Tech slumps on 3Q estimate and 4Q outlook Wednesday, 17 Oct 2012 | 8:10 PM ET

    NEW YORK-- Align Technology Inc., which makes the Invisalign clear braces system, slumped Wednesday after the company gave disappointing estimates for its third-quarter results and offered a weak fourth-quarter forecast. Align Technology shares skidded $7.05, or 20 percent, to $28.36 in aftermarket trading following the announcement.

  • NY philanthropist freed on bail after court ruling Wednesday, 17 Oct 2012 | 8:06 PM ET

    NEW YORK-- An opera-loving philanthropist convicted in New York of a multimillion-dollar fraud has been freed on bail to await the outcome of his appeal. Alberto Vilar was freed Wednesday on $10 million bail from a federal lockup in Fort Dix, N.J. He'll be required to wear an electronic bracelet, as he was before his November 2008 conviction.

  • MannKind Corp. plans public stock offering Wednesday, 17 Oct 2012 | 6:40 PM ET

    VALENCIA, Calif.-- Shares of MannKind Corp. fell sharply in after-hours trading Wednesday after the diabetes drug developer said it is planning a public offering of stock and warrants. MannKind said that it intends to sell common shares and warrants to purchase common shares in the underwritten offering.

  • Sen. Mitchell appointment in Calif. blast opposed Wednesday, 17 Oct 2012 | 5:57 PM ET

    Eight people died and 38 homes were destroyed in the gas-fueled inferno that tore through the bedroom community of San Bruno on Sept 9, 2010 after one of PG&E's pipelines ruptured.

  • Intel, Dean Foods, PulteGroup are market movers Wednesday, 17 Oct 2012 | 5:53 PM ET

    NEW YORK-- Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and Nasdaq Stock Market:. Quest Diagnostics Inc., down $3.62 at $59.75. Dean Foods Co., up $1.92 at $16.96.

  • Surge in US home construction could lift economy Wednesday, 17 Oct 2012 | 5:33 PM ET

    U.S. home construction is making a comeback that could invigorate the economy's still-weak recovery. Builders last month started construction on single-family houses and apartments at the fastest rate in more than four years, the Commerce Department said Wednesday.

  • American Express profit inches higher in 3Q Wednesday, 17 Oct 2012 | 4:21 PM ET

    LOS ANGELES-- American Express Co. said Wednesday that its net income rose 1 percent in the third quarter, aided by lower expenses and increased spending by the credit card issuer's customers. In the second quarter, American Express' revenue grew 5 percent from a year earlier.

  • California foreclosure notices fall to 5-year low Wednesday, 17 Oct 2012 | 4:15 PM ET

    SAN DIEGO-- Home foreclosure activity in California fell to a new five-year low in the third quarter as rising prices eased pressure on homeowners and lenders, a research firm said Wednesday.

  • Big Bird costumes hot sellers for Halloween Wednesday, 17 Oct 2012 | 3:28 PM ET

    NEW YORK-- Can't figure out how to dress as a binder full of women for Halloween? The Yellow One is flying off the shelves after Mitt Romney's threat to do away with government support for PBS.

  • St. Jude falls on FDA concerns, sales estimate Wednesday, 17 Oct 2012 | 3:26 PM ET

    NEW YORK-- Shares of St. Jude Medical Inc. declined Wednesday after the medical device maker cut its 2012 revenue estimate and said it may get a warning from federal regulators about a defibrillator plant in California.

  • Earnings roundup: St Jude Medical, Amphenol Wednesday, 17 Oct 2012 | 3:21 PM ET

    Among the earnings stories for Wednesday, Oct. 17, from The Associated Press:. _ Medical device maker St. Jude Medical Inc. reported third-quarter earnings that beat expectations, though company shares slumped as the executives warned that the company could receive a regulatory warning over a California manufacturing plant.

  • Syria's wealthy businesses feel civil war squeeze Wednesday, 17 Oct 2012 | 3:17 PM ET

    CAIRO-- Syria's wealthy, long cultivated by President Bashar Assad as a support for his regime, are seeing their businesses pummeled by the bloody civil war. Assad may not have lost the backing of Syria's business elite, but some are losing faith.

  • Parker Hannifin to buy Sea Recovery, no terms Wednesday, 17 Oct 2012 | 3:10 PM ET

    CLEVELAND-- Parker Hannifin Corp., which makes industrial hoses, airplane wheels and other products, said Wednesday that it has agreed to buy Sea Recovery from Denmark's Danfoss A/S. Cleveland- based Parker Hannifin will assume ownership of the business on Nov. 1. Parker Hannifin shares rose $1.85, or 2.3 percent, to $83.82 in afternoon trading Wednesday.