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  • April 17- A large study of Bristol-Myers Squibb Co's Opdivo treatment has been halted after proving the drug is effective against the most common form of lung cancer, the company said, positioning the medicine for far wider use than its already approved lung cancer and melanoma indications. AstraZeneca Plc, Pfizer Inc and other drugmakers are developing their...

  • PHILADELPHIA— A worker is dead after an 80- foot fall at a construction site in Philadelphia. City police told WPVI-TV that the accident occurred shortly after 8 a.m. Friday in the 2900 block of Chestnut Street. They say he was pronounced dead at Presbyterian Hospital.

  • At a Glance: Internet TV options Friday, 17 Apr 2015 | 1:26 PM ET

    Next-day access to shows for $2 or $3 an episode. Live offering: Local stations in 14 markets with CBS- owned stations. Monthly price: Starts at $20.

  • Glaxo recalls flu vaccine due to potency problem Friday, 17 Apr 2015 | 1:24 PM ET

    WASHINGTON— GlaxoSmithKline is recalling remaining doses of a popular four-in-one flu vaccine because of effectiveness problems. But Glaxo said in a letter it "cannot rule out potential suboptimal protection" in people who received the vaccine in early January or later. More than 99 percent of the vaccines were distributed in 2014, before the product began...

  • WASHINGTON— An emergency order requiring trains hauling crude oil and other flammable liquids to slow down as they pass through urban areas and a series of other steps to improve the safety were announced Friday by the Department of Transportation. There have been a series of fiery oil train explosions in the U.S. and Canada in recent years, including one just...

  • Crown tops 1Q profit forecasts Thursday, 16 Apr 2015 | 5:07 PM ET

    PHILADELPHIA _ Crown Holdings Inc. on Thursday reported first-quarter earnings of $44 million. The average estimate of eight analysts surveyed by Zacks Investment Research was for earnings of 51 cents per share. Seven analysts surveyed by Zacks expected $2.08 billion.

  • HARRISBURG, Pa.— A candidate who received the largest single campaign contribution reported so far in Pennsylvania's Supreme Court race said Thursday that the $500,000 will make him competitive in the May 19 Republican primary. Adams County Judge Mike George said Thursday that the donor, businessman Gary Lowenthal, is an old friend who wanted to help George...

  • WASHINGTON— Factories in the Philadelphia region got a bit busier in April compared to March. But the Federal Reserve Bank of Philadelphia says production and shipments are still at low levels. The Philadelphia Fed's index of regional factory activity ticked up to 7.5 this month from 5 in March.

  • Audit finds wide mismanagement at Philadelphia VA Wednesday, 15 Apr 2015 | 10:18 AM ET

    WASHINGTON— Unreasonable workloads and poor leadership at the Veterans Affairs facility in Philadelphia have led to mismanagement and delays in handling veterans' disability and pensions claims, according to a government audit released Wednesday. In a blistering 79- page report, the VA's inspector general cites a litany of problems, all part of a rush to...

  • Court: Wal-Mart can exclude gun sales proposal from proxy Wednesday, 15 Apr 2015 | 3:01 AM ET

    DOVER, Del.— A federal appeals court has ruled that Wal-Mart can exclude from its 2015 proxy statement a shareholder's proposal to review the sale of some guns. The appeals court in Philadelphia on Tuesday reversed a 2014 ruling ordering Wal-Mart to include the proposal from Trinity Wall Street Church in New York. The Episcopal parish wants shareholders to vote...

  • April 14- A federal appeals court on Tuesday said Wal-Mart Stores Inc will not be required to let shareholders vote at its annual meeting on a proposal to force tighter oversight of its sale of high-capacity guns. The proposal by Trinity Church, a historic church in downtown Manhattan, would have required Wal-Mart's board to more closely examine the sale of...

  • House GOP property tax cut sponsor outlines proposal Tuesday, 14 Apr 2015 | 3:02 AM ET

    Tom Wolf's property-tax relief plan outlined the details Tuesday and said the GOP blueprint would provide a straightforward shift of nearly $5 billion to slash local tax bills. Stan Saylor told the House Finance Committee. Saylor proposes increasing the state personal income and sales taxes, as well as using $600 million in expected gaming revenue, to...

  • Pep Boys reports 4Q loss Monday, 13 Apr 2015 | 5:07 PM ET

    PHILADELPHIA _ Pep Boys-Manny Moe& Jack on Monday reported a loss of $26.7 million in its fiscal fourth quarter. The Philadelphia- based company said it had a loss of 50 cents per share. Pep Boys shares have declined 2 percent since the beginning of the year.

  • PHILADELPHIA, April 12- When Justin Becker moved into a new home in south Philadelphia, he set the TV and video games in the unfinished basement, leaving his three children free to go down and watch when they wanted. The board games stayed upstairs in the living room. Hasbro Inc, maker of old standbys like Monopoly and Risk, says that revenue for its line of games...

  • March 31- Comcast Corp Chief Financial Officer Michael Angelakis will leave his position to head a new investment arm with up to $4.1 billion to invest in growth-oriented companies, Comcast said on Tuesday. Philadelphia- based Comcast, which already has a venture capital arm through Comcast Ventures, said the new company would begin operations in 2015 or early...

  • NEW YORK, March 31- U.S. "We are also getting a little bit of safe-haven buying on the margin," said Guy LeBas, chief fixed-income strategist at Janney Montgomery Scott in Philadelphia. Uncertainty over the talks in Switzerland on hammering out a nuclear deal between Iran and global powers was also driving some bids for Treasuries, according to Vishal Khanduja,...

  • NEW YORK, March 31- U.S. "We are also getting a little bit of safe-haven buying on the margin," said Guy LeBas, chief fixed-income strategist at Janney Montgomery Scott in Philadelphia. Anxieties in Europe over Greece's finances were keeping the euro on track for its biggest losing quarter since the currency's introduction as central bankers in the region buy...

  • NEW YORK, March 31- U.S. stocks retreated on Tuesday from the previous session's rally, though major indexes were headed for a positive first quarter, while the euro was on track for its biggest quarterly fall as worries about Greece kept the currency under pressure. The European Central Bank's one-trillion-euro economic stimulus program, launched this month,...

  • NEW YORK, March 31- U.S. stock fell on Tuesday in a modest retreat from the previous session's sharp rally, though major indexes remained on track for a positive first quarter and the S&P 500 was set for its ninth straight quarterly rise. Energy shares will be in focus as crude oil fell 1.4 percent to $48 per barrel, sending the S&P Energy index down 1 percent and Exxon...

  • Stanford's victims accused the SEC of negligence for having waited until 2009 to uncover the Ponzi scheme, despite having had evidence of it as early as 1997.. But the court said the SEC had discretion to decide how to enforce securities laws, and could not be liable for certain misrepresentations. Victims claimed that the SEC thought Stanford's business was a...