* "Platinum belt" death toll nears 50
* Rand falls as labour unrest spreads
* Shell declares "force majeure"
(Updates with Amplats firings)
By Agnieszka Flak
JOHANNESBURG, Oct 5 (Reuters) - The world's largest platinum producer, Anglo American Platinum, fired 12,000 workers taking part in a three-week illegal strike on Friday, following through on tough talk over wildcat stoppages in South African mines.
Two months of labour unrest has spread from mines to other parts of Africa's biggest economy, causing political problems for President Jacob Zuma and his ruling African National Congress (ANC), the veteran liberation movement long closely tied to unions.
Shell said on Friday it could not honour fuel delivery contracts around Johannesburg because of a two-week truckers' strike. Police shot dead another striking miner overnight, taking the death toll to 48 in the worst labour unrest since the end of apartheid.
The rand fell two percent to within sight of a three-year low against the dollar amid fears the (ANC) is powerless to manage the spreading labour unrest.
Zuma has been criticised for his low-key response, especially after police killed 34 strikers at Lonmin's Marikana platinum mine on Aug. 16.
In a speech to business leaders late on Thursday he put a positive spin on the situation, stressing that since the end of white-minority rule South Africans have shown "the capacity to overcome difficulties when we work together".
"We should not seek to portray ourselves as a nation that is perpetually fighting," he said.
However, with an ANC leadership run-off looming in December, Nelson Mandela's 100-year-old liberation movement is preoccupied with its own divisions and Zuma is unlikely to take any action to stabilise the economy that could upset his political allies in the unions.
"In the build-up to the election, the government is unlikely to come out with any clear policy directives," said Simon Freemantle, an analyst at Standard Bank in Johannesburg.
Reflecting such concerns, Moody's cut South Africa's credit rating last week, and the intensifying strikes in the mining sector and elsewhere are raising very real fears of a big hit to already sluggish economic growth for this year.
Finance Minister Pravi Gordhan has already said he will have to cut his 2.7 percent growth forecast for 2012 when he delivers an interim budget on Oct. 24.
More than 75,000 miners, or 15 percent of the workforce in a sector that accounts for 6 percent of output, have been out on unofficial strikes and tensions with security forces and mining bosses are running high.
Near the "platinum belt" city of Rustenburg, 120 km (70 miles) northwest of Johannesburg, workers said a miner was killed by a rubber bullet fired by police overnight.
"He was shot here by the police," Mbubhu Lolo, a striker from Anglo American Platinum, also known as Amplats, told Reuters, pointing to his midriff.
Police would not confirm the cause of the death, although the ground nearby was strewn with spent rubber-bullet shell casings and teargas canisters after clashes involving water cannon the previous evening.
On Friday, protesters in a shanty town near the Amplats mine barricaded streets with rocks and burning tyres, watched by a contingent of more than 30 riot police backed by armoured vehicles.
Earlier in the week, strikers torched an Amplats training centre and two conveyor belts, making it harder to restart operations when it does manage to resolve the standoff.
AngloGold Ashanti , South Africa's biggest bullion producer, has lost virtually all local production due to wildcat strikes, while rivals Gold Fields and Harmony Gold
have also taken a hit.
Around 300 strikers at Kumba Iron Ore have also blockaded the company's giant Sishen iron ore mine in the remote Northern Cape province.
The mining sector unrest has shaken investor confidence, and signs of it spreading into manufacturing - which accounts for 15 percent of output - and an expanding truckers' strike have caused even more alarm.
"There is fuel available across the country, so the issue is not fuel supply, but the challenge is delivering it safely to our retail sites," oil giant Shell said after invoking a "force majeure" clause that allows it to break contracts due to situations beyond its control.
Other petrol companies are holding their breath, especially around the commercial hub Johannesburg, but have not yet followed Shell's move.
Raising the stakes in its two-week stoppage by 20,000 truckers, the SATAWU transport union said it wanted co-workers on South Africa's railways and ports to strike next week, a development that would affect coal and other mineral shipments.
Coal output from one of the world's biggest suppliers has so far been unaffected but any disruption could hit power utility Eskom, which is already struggling to prevent a repeat of a 2008 power crisis when the grid nearly collapsed. Some 85 percent of South Africa's electricity is generated by coal-fired plants.
Many supermarkets and logistics firms are running on back-up plans because of the truckers' strike. U.S. car giant General Motors said production at its Port Elizabeth plant on the south coast has been affected.
Toyota suffered a four-day wildcat outage at its Durban plant, although workers returned on Friday after securing a 5.4 percent pay rise.
"As far as I know, the guys have been pitching up for work and production has restarted," Toyota SA spokesman Leo Kok said.
(Additional reporting by David Dolan and Wendell Roelf; Writing by Ed Cropley; Editing by Will Waterman and Peter Graff)
Keywords: SAFRICA STRIKES/