U.S. stock index futures trimmed their gains Wednesday following a weaker-than-expected private sector employment report and ahead of the outcome of the Federal Reserve's two-day meeting.
The U.S. private sector added 119,000 jobs in April, according to the ADP National Employment Report, well below economists' expectations for an increase of 150,000 jobs. It was the smallest gain since last September.
The ADP report came ahead of the government's widely-watched monthly employment report, which is expected to show 150,000 new non-farm jobs were added in April, according to an estimate from Reuters.
Major averages posted robust gains of more than 1.5 percent across the board in April, with the S&P 500 setting a record intraday high.
Also on the economic front, U.S. manufacturing growth slipped to 52.1 in April from 54.6 in March, the lowest final reading in six months, according to financial data from Markit. A reading above 50 indicates expansion.
April's Institute of Supply Management report is scheduled to be reported at 10 am ET and will be monitored closely after Tuesday's disappointing Chicago PMI numbers. Economists polled by Reuters predict the increase in manufacturing activity slowed slightly to 51.0 in April, down from 51.3.
Later this afternoon, investors will focus on what the central bank says in its policy statement, and whether it will ramp up its asset-purchase program in light of recent weaker-than-expected economic data. The post-meeting statement is due at 2 pm ET.
"Markets will have to read between the lines as there will not be a Bernanke press conference to follow this time," said Deutsche Bank strategist Jim Reid, in a research note on Wednesday.
"The tone will likely be slightly more dovish given the recent softening in activity and inflation data, but with things not yet weak enough to warrant a change in their policy stance."
At its last meeting in March, the Fed said it would keep its main interest rate at a record low of between zero and 0.25 percent, until the unemployment rate falls below 6.5 percent.
Among earnings, Comcast gained after the cable television provider posted higher quarterly earnings, thanks to strength on the cable side of its business. Comcast is the parent company of NBCUniversal.
To date, a little over 60 percent of S&P 500 companies have posted quarterly results, with 69 percent of firms topping earnings expectations, according to Reuters. If all remaining companies post results inline with estimates, earnings will be up 4 percent on first quarter 2012.
Meanwhile, only 44 percent of companies have beaten revenue forecasts. On average, sales have come in 1 percent below estimates.
Meanwhile, the European Central Bank meets on Thursday, and is widely expected to cut interest rates to give the frail euro zone economy a boost. Most European markets are closed on Wednesday for the May Day public holiday, but London-listed stocks are trading.
"The stock-pickers market will be tested over the coming days. It certainly feels like there is a 'calm before the storm' effect at the moment," wrote Evan Lucas, market strategist at IG, in a note."Macro data has to start showing signs of stabilizing, or central banks have to respond to the data being printed. Without this, a correction is on."
(Read More: Why ECB Rate Cut Could Be Too Little, Too Late)
Weekly mortgage applications gained last week, lifted by demand for refinancings as interest rates slid, according to the Mortgage Bankers Association.
—By CNBC's JeeYeon Park (Follow JeeYeon on Twitter:
Coming Up This Week:
WEDNESDAY: ISM mfg index, construction spending, oil inventories, FOMC mtg announcement, auto sales, McGraw-Hill shareholder mtg, New York Times shareholder mtg, PepsiCo shareholder mtg, JCPenney Martha Stewart shops open; Earnings from Facebook, Visa, Allstate, CBS, Marriott, MetLife, Yelp
THURSDAY: Challenger job-cut report, ECB announcement, international trade, jobless claims, productivity & costs, natural gas inventories, Fed balance sheet/money supply, DirecTV shareholder mtg, UBS shareholder mtg, UPS shareholder mtg, Verizon shareholder mtg; Earnings from GM, Royal Dutch Shell, Sanofi, Kellogg, Beazer Homes, AIG, Gilead Sciences, Kraft Foods
FRIDAY: Nonfarm payrolls, factory orders, ISM non-mfg index, AOL shareholder mtg, Blackstone analyst mtg; Earnings from Berkshire Hathaway
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