The pan-European FTSEurofirst 300 Index provisionally closed down 0.8 percent to 1,214.64 points, with all key European bourses in the red. The Spanish IBEX fell 1.9 percent, closed the FTSE 100 was down 0.3 percent — it has now fallen 3.5 percent since the start of the month.
The basic resources sector closed provisionally down 1.40 percent. Shares of U.K.-based miner BHP Billiton slipped by 1.94 percent after earnings missed forecasts on Tuesday, with a 15 percent fall in second-half profit.
(Read More: BHP Billiton profit drops 15% despite cost cuts)
Shares of Glencore Xstrata fell 2 percent after it wrote down the value of assets inherited from Xstrata by $7.7 billion. It also announced a 9 percent drop in core profit in the first set of full results since the two companies merged.
(Read More: Glencore takes $7.7 billion hit on Xstrata assets)
In stocks news, Barclays shares dropped 0.67 percent after a U.S. appeals court said investors may revive a lawsuit accusing the U.K. bank of misleading them in a 2008 stock offering about its subprime mortgage exposure.
(Read More: Barclays faces renewed lawsuit over subprime)