In Singapore, 37 percent of those polled said they had been woken up during the night by a telephone call from a colleague or clients and two thirds said they have had their annual leave interrupted by work, according to eFinancial Careers, whose clients include major banks such as HSBC, Morgan Stanley and regional heavyweight DBS.
Over three quarters of those surveyed said their weekends have also been disrupted by work.
(Read more: BofA intern dies after reportedly working 3 straight days)
Recruiters and human resource groups have called for changes to guidelines and working practices following the death earlier this month of Bank of America Merrill Lynch intern Moritz Erhardt.
Erhardt, who was an intern in BofA's investment banking division, collapsed at his London home after reportedly working until 6 a.m. three days in a row.
A culture of long working hours and pressure could make it difficult for the financial sector to recruit the brightest graduates, according to McFerran.
(Read more: Brussels interns protest working conditions, lack of pay)
"The current crop of graduates coming out of university today are less impressed by financial services as a career option… perhaps the best and the brightest are saying: is this what we want?," he said.
A quarter of professionals in Singapore's financial services sector work on a shift basis, the survey showed. It was conducted in July and almost 1,740 professionals took part in the poll.
— By CNBC.Com's Dhara Ranasinghe; follow her on Twitter