When asked whether he regretted the public firing, Armstrong told "Squawk on the Street" that "the way it was handled specifically, I probably would have done it differently."
"But in the moment where I am trying to communicate with 1,000 people about the future of our company … everybody in that meeting knew it was a confidential meeting," he added. "I would not apologize about the way that I communicate with the employees."
Although the conference call was originally intended to boost morale, Armstrong said that several hundred jobs hung "in the balance" and that the details of the meeting were non-public information.
Armstrong also gave insight into the company's long-term strategy, where he plans to make AOL a "facilitator" of online advertising, as well as on-demand and live video on the web.
"It's really a pivot point for the industry," he said. "It's really about automation … changes are happening in the advertising industry, AOL is at the forefront of that."
On Monday, AOL hosted an event for advertisers, unveiling the company's plans to roll-out programmatic ad buying, which he envisions will increase transparency while creating faster transaction speeds, as well as more transactions.
"If you're a corporation trying to reach consumers, this is an important week for you to understand where the industry is going and we want to help you plan for that," he said.