Twitter hit an all-time high as it continued to climb after unveiling an advertising product called Tailored Audiences.
Facebook rose on bullish comments from Morgan Stanley.
AbbVie rose after saying a late-stage trial of its experimental hepatitis-C therapy showed a 96 percent improvement rate.
Gilead Sciences declined a day after its own hepatitis-C pill was approved by the FDA.
Johnson & Johnson and Novartis fell after being fined by the European Union for blocking the sale of a cheaper generic painkiller.
Broadcom gained after guiding fourth-quarter revenue above street forecasts.
PVH climbed after posting better-than-expected third-quarter results.
Burlington Stores fell after the discount-retailer forecast slower growth in same-store sales for the holiday season.
Analogic slid after the biotech reported weaker-than-expected first-quarter results, due to lower sales in its medical imaging unit.
Quest Diagnostics declined after Bank of America/Merrill Lynch cut the stock to underperform.
(Read More: See CNBC's Market Insider Blog)
—By CNBC's Rich Fisherman.
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