"Tomorrow morning's commute looks to be pretty unseemly for them," he added, saying that it would likely strike the Northeast at 8 p.m. Tuesday.
It "will be a rough one in Boston tomorrow morning," he said. Major cities like New York, Philadelphia and Washington, D.C., will likely avoid the worst of the snow, but the potential for freezing rain and ice is high.
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Smashing through the Plains on Tuesday, the storm could hit Kansas and Nebraska with more than 12 inches of snow before moving north to dump between five and eight inches on Chicago, Cleveland, Indianapolis and Detroit, Roth said. Schools across Kansas and Missouri have closed, and flight cancellations are mounting ahead of the storm.
The National Weather Service issued winter storm warnings across 15 states early Tuesday from the Rockies to southern Maine.
At least two deaths and one serious injury could be blamed on Monday's storm and its cleanup: In western Kentucky, where the snow began to fall Sunday, a 24-year-old man died after his car skidded into a snowplow, officials told NBC affiliate WFIE.
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Meanwhile in New York, a 73-year-old man was struck and killed by a snowplow that was backing up on a Brooklyn street, police told NBC New York.