Corium International fell in its market debut after the drug delivery systems provider priced 6.5 million shares at $8.
Pandora fell after initially opening higher as the online radio company announced listeners increased in March.
Vivus lost ground after Piper Jaffray downgraded the stock to "underweight" and reduced its price target to $3 from $8, citing a bearish outlook for its anti-obesity drug.
Liquidity Services slid after the company withdrew from Defense Logistics Agency bidding auction to purchase, manage and sell surplus assets of the Department of Defense.
Twitter moved lower despite the Turkish government saying it is restoring access to the site, a day after a high court ruling against the ban.
Intel moved higher after Piper Jaffray upgraded the stock to "overweight" from "neutral" with a price target of $30, citing PC market stabilization.
CACI International fell after the company cut its fiscal 2014 earnings and sales outlook.
First Republic Bank, Extra Space Storage lost ground after Goldman Sachs removed both companies from its "conviction buy" list. Goldman also downgraded US Bancorp to "neutral."
Amgen moved lower after the company said it was ending a marketing agreement with GlaxoSmithKline for its osteoporosis drug outside the U.S.
Walgreen gained ground after the drugstore chain said March sales grew 4.5 percent from a year ago.
Online brokers Charles Schwab, Etrade and Ameritrade all moved lower after Charles Schwab said high frequency trading is a growing cancer to the stock market that needs to be addressed.
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