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Europe closes mixed; AstraZeneca tanks

European closed mixed on Monday, with traders shunning riskier assets amid concerns over stock valuations, policy action from the European Central Bank and upcoming elections in the region.

Meanwhile, U.S. stocks had opened lower on Monday, as investors pulled back after major highs and mixed economic data.

Symbol
Name
Price
 
Change
%Change
Volume
FTSE
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DAX
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CAC 40
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IBEX 35
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The pan-European FTSEurofirst 300 Index closed provisionally down 0.2 percent at 1,359.51 points, after Italy's FTSE MIB showed strong selling.

The FTSE MIB closed down unofficially 1.6 percent. European parliamentary elections are set to be contested at the end of the week, and Italy's prime minister, Matteo Renzi, is thought to be vulnerable, after weak economic growth data.

France's CAC and Germany's DAX closed provisionally up 0.3 percent and 0.4 percent respectively, after wavering throughout the day.

The health care sector saw the biggest losses. AstraZeneca shares closed down around 11 percent after the company rejected an improved offer from U.S. drugmaker Pfizer.

AstraZeneca pulled down the U.K's FTSE100, which closed provisionally down 0.1 percent.

Read MoreAstraZeneca Chair:Shareholders can 'vote me away'

Mining shares also suffered after disappointing house price data out of China fueled concerns the world's second biggest economy was slowing.

In individual stock news, Deutsche Bank shares closed down around 2 percent on Monday after it announced plans to raise 8 billion euros with a fresh share sale.

The German lender is attempting to bolster its capital position in the face of increased regulation following the financial crash of 2008. The Qatari royal family is being lined up as a major new investor, the bank said in statement.

Read MoreQatar royals to takemajor stake in Deutsche Bank

Budget airline Ryanair posted its first drop in full-year profits in five years on Monday and warned that larger planes next year would mean it would have more seats to fill. However, its shares closed up around 10 percent, helped along by a special dividend and analysts saying that estimates from Ryanair for the forthcoming year were "conservative."

Dixons Retail closed up around 2 percent after the U.K. retailer announced that it was selling its European operations to a Slovakian firm.

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Symbol
Price
 
Change
%Change
FTSE
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DAX
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CAC 40
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PFE
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AZN
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RY4B
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STOXX600
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DXNS
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.SXDP
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DBK
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DJIA
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FTSE MIB
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DJ STOXX BR
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.FTSESP
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FTSE EUR 300
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