**MERCK& CO INC, $45.95, down 2 pct. **TITAN PHARMACEUTICALS INC, $0.46, down 73 pct. **NEUTRAL TANDEM INC, $4.57, up 53 pct.
The UK Small Cap index closes up 0.1 percent to lag both the FTSE 100, up 0.3 percent, and the FTSE 250, ahead 0.6 percent.
LONDON, May 1- Britain's top shares gained in thin trade on Wednesday as banks rose further on expectations of more monetary easing from the European Central Bank.
NEW YORK, May 1- Regeneron Pharmaceuticals Inc:. *Shares as shares of Allergan slide after co says vision drug approval. *Shares up 13.2 percent as shares of Allergan slide after co says.
NEW YORK, May 1- Regeneron Pharmaceuticals Inc:. *Shares halted, last up 14.3 percent. ( (New York Treasury Desk; Tel: 223 6300)).
**MERCK& CO INC, $44.76, down 5 pct. **TITAN PHARMACEUTICALS INC, $0.34, down 80 pct. U.S. health regulators rejected an experimental drug to treat opioid addiction made by Titan Pharmaceuticals and asked for additional data showing it works, the company said.
LONDON, May 1- Britain's top share index pared gains and briefly turned negative on Wednesday after several U.S. data reports missed expectations, taking the wind out of growth sensitive stocks. U.S. companies hired the smallest number of employees in seven months in April while manufacturing growth slowed, data showed.
EUROPEAN COMPANIES BG GROUP PLC Q1 SIEMENS AG Q2 DEUTSCHE LUFTHANSA AG Q1 METRO AG Q1 SANOFI SA Q1 ORKLA ASA Q1 SWISS RE AG Q1 KONINKLIJKE DSM NV Q1 HUGO BOSS AG Q1 INFINEON TECHNOLOGIES AG Q2 REXEL SA Q1 STATOIL ASA Q1 SWISSCOM AG Q1 BEIERSDORF AG Q1 BRITISH SKY BROADCASTING GROUP Q3 INMARSAT PLC Q1 RANDGOLD RESOURCES LTD Q1 ROYAL DUTCH SHELL PLC Q1 SMITH& NEPHEW PLC Q1 VERBUND AG Q1 BAYERISCHE MOTOREN WERKE AG Q1 GRIFOLS SA Q1 COFINIMMO SA Q1 DANSKE BANK A/S Q1 SHIRE PLC Q1 VALLOUREC SA Q1 U.S.
NEW YORK, May 1- T-Mobile US Inc shares rose 3 percent in their debut on the New York Stock Exchange on Wednesday, after the company was created by the merger of MetroPCS Communications and Deutsche Telekom AG's U.S. unit T-Mobile USA.
**MERCK& CO INC, $44.76, down 5 pct. **TITAN PHARMACEUTICALS INC, $0.34, down 80 pct. **NEUTRAL TANDEM INC, $4.12, up 38 pct.
*FDA asks for more data on Probuphine. Clinical data showed Probuphine to be more effective than placebo in curbing addiction, but an outside panel of experts to the FDA said in March that the data were not particularly robust and suggested the proposed Probuphine dose could be too low.
*FDA asks for more data on Probuphine. Clinical data showed Probuphine to be more effective than placebo in curbing addiction, but an outside panel of experts to the FDA said in March that the data were not particularly robust and suggested the proposed Probuphine dose could be too low.
Wall Street was set for a slightly lower open on Wednesday, weighed by weak results from Merck and as investors waited to hear from the U.S. **MERCK& CO INC, Tuesday close $47, down 5 pct premarket. **CHESAPEAKE ENERGY CORP, Tuesday close $19.54, up 5 pct premarket.
U.S. stock index futures were flat ahead of the outcome of the Federal Reserve's two-day meeting and after the S&P 500 set a fresh all-time high in the previous session.
NEW YORK, May 1- Sourcefire Inc:.
NEW YORK, May 1- MasterCard Inc:. *Shares down 2.1 percent in premarket trading after results. ( (New York Treasury Desk; Tel: 223 6300)).
Wall Street was set for a flat open on Wednesday as investors waited to hear from the U.S. **MERCK& CO INC, Tuesday close $47, down 5 pct premarket. **CHESAPEAKE ENERGY CORP, Tuesday close $19.54, up 5 pct premarket.