Genzyme Corp. said Wednesday it is canceling development of a successor to its kidney treatment Renvela, as the new drug did not work much better than Renvela.

An experimental drug for patients genetically disposed to extreme high cholesterol being developed by Isis Pharmaceuticals Inc and Genzyme Corp significantly lowered cholesterol in a pivotal late-stage study, according to data presented on Tuesday.

Genzyme Corp. said Monday the Food and Drug Administration will not approve the potential Pompe disease treatment Lumizyme until the company fixes manufacturing problems at the company's Boston-area facility.

Stainless steel fragments, non-latex rubber and fiber-like material have been found in some drugs made by Genzyme Corp, dealing another blow to a company already struggling with manufacturing problems.

Stocks resumed their ascent Friday, after snapping the week's winning streak on Thursday, as investors braced for a volatile day due to quadruple witching.

The Dow and S&P snapped their winning streaks Wednesday as disappointing earnings from two of Wall Street's biggest names overshadowed another round of earnings beats.

Stocks wobbled Wednesday as a slew of earnings beats, including one from Pfizer, were encouraging but disappointing reports from two of Wall Street's biggest names dragged on the market.

Stocks wobbled Wednesday as a slew of earnings beats, including one from Pfizer, were encouraging but disappointing reports from two of Wall Street's biggest names dragged on the market.

Futures indicated a lower open for Wall Street Wednesday as cautious words from Federal Reserve Chairman Ben Bernanke and Yahoo's missing revenue expectations lent to investors taking profits.