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  • April 23- Spectrum Pharmaceuticals Inc said it expects to seek U.S. marketing approval for its blood cancer drug in the third quarter, after the treatment was shown to be safe and effective in a key mid-stage trial. Roth Capital Partners analyst Joseph Pantginis said he expects CE-Melphalan to receive full approval next year.

  • *Senate must approve legislation by May 19. ROME, April 23- Italian Prime Minister Matteo Renzi easily won a confidence vote on Wednesday over his plans to ease rules for companies that hire temporary workers, part of a broader plan to overhaul labour regulations. The decree must be approved by the Senate by May 19 to become a permanent law.

  • *AT&T falls after results, but Boeing rallies. *Amgen drags biotech lower, but Gilead gains. NEW YORK, April 23- U.S. stocks edged lower on Wednesday as weakness in AT&T and biotech names inspired investors to take profits following six straight days of gains, though a rally in Boeing limited losses.

  • OTTAWA, April 23- Canada will require that the use of older rail cars for carrying crude oil be phased out within three years, even though the United States has yet to make such a rule change, according to documents seen by Reuters on Wednesday.

  • TOKYO, April 23- Toyota Motor Corp kept its position as the world's best-selling car maker in the first quarter of 2014, beating rivals Volkswagen AG and General Motors Co after it sold record 2.58 million vehicles globally. Toyota's group sales include figures from minicar maker Daihatsu Motor Co along with truck and bus maker Hino Motors Ltd..

  • NEW YORK/ LONDON, April 23- Gold prices were little changed on Wednesday, holding above a key technical support near $1,275 an ounce, though the metal is vulnerable to further losses as investor demand remains slack, analysts said.

  • *Results from ARM, Ericsson cast shadow on tech earnings. LONDON, April 23- European shares snapped a three-day winning streak on Wednesday, with tech stocks hit by disappointing results from Ericsson and chip designer ARM Holdings, casting fresh shadows on the sector's earnings picture.

  • India, Iran in deal to ease sting of sanctions Wednesday, 23 Apr 2014 | 11:34 AM ET
    This handout image supplied by the IIPA (Iran International Photo Agency) shows a view of the reactor building at the Russian-built Bushehr nuclear power plant.

    India is set to pay Iran $1.65 billion under an interim nuclear deal that eases sanctions and gives Tehran access to $4.2 billion in blocked funds.

  • INDIA PREPARES TO PAY IRAN 3 TRANCHES OF $550 MLN EACH FOR OIL IMPORTS UNDER INTERIM NUCLEAR DEAL- SOURCES.

  • IRAN WANTS PAYMENTS IN OMANI RIALS IN CENTRAL BANK OF IRAN'S ACCOUNT WITH BANK MUSCAT- SOURCES.

  • India to make May-July oil payments to Iran - sources Wednesday, 23 Apr 2014 | 11:24 AM ET

    NEW DELHI, April 23- India is set to pay Iran $1.65 billion over the next three months under an interim nuclear deal that eases sanctions on Tehran and gives it access to $4.2 billion in blocked funds, four sources with knowledge of the matter said.

  • UPDATE 1-Kenyan shilling firms but further losses seen Wednesday, 23 Apr 2014 | 11:12 AM ET

    "It came off a bit central bank mop-ups of the shilling, and also... there were some inflows, coming to settle the bond," said John Muli of African Banking Corporation. The Central Bank of Kenya said it received bids worth 30.27 billion shillings for the 15 billion shillings worth of paper on offer.

  • NEW YORK, April 23- The U.S. dollar weakened against the euro and yen on Wednesday, undermined by a decline in U.S. equity prices and Treasury yields and finding little support from a slower-than-expected expansion in the U.S. manufacturing sector.

  • Facebook gets U.S. antitrust approval to buy Oculus Wednesday, 23 Apr 2014 | 11:09 AM ET

    WASHINGTON, April 23- Social network giant Facebook Inc has won U.S. antitrust approval to buy Oculus VR Inc, a two-year-old maker of virtual reality goggles, the Federal Trade Commission said on Wednesday. Facebook said on March 25 that it planned to buy Oculus for $2 billion in its first-ever hardware deal.

  • The 2nd U.S. Circuit Court of Appeals in New York said a lower court judge erred in concluding that a U.S. anti-racketeering law, the Racketeer Influenced and Corrupt Organizations statute, cannot apply to foreign enterprises or to conduct outside the United States.

  • *Ukraine says' Easter truce' is over. *Survey shows China manufacturing decline slows. LONDON, April 23- Brent oil fell below $109 on Wednesday after weekly data showed U.S. crude inventories hit a record high, though prices found some support from the unfolding crisis in Ukraine.

  • METALS-Nickel dips after 14-month high, Chinese data Wednesday, 23 Apr 2014 | 10:57 AM ET

    The ban on exports of unprocessed minerals by Indonesia, the world's biggest nickel ore supplier, was felt sharply last month when its shipments to top buyer China fell to less than a million tonnes from an average of 3.4 million tonnes a month last year.

  • WASHINGTON, April 23- Sales of new U.S. single-family homes tumbled to their lowest level in eight months in March, dealing a setback to the housing market recovery. The Commerce Department said on Wednesday sales dropped 14.5 percent to a seasonally adjusted annual rate of 384,000 units, declining for a second consecutive month.

  • NEW YORK, April 23- U.S. The Commerce Department said sales of new U.S. single-family homes dropped 14.5 percent to a seasonally adjusted annual rate of 384,000 units in March, declining for a second consecutive month.

  • CEOs back country-by-country tax reporting - survey Wednesday, 23 Apr 2014 | 10:38 AM ET

    LONDON, April 23- Most chief executives globally would support the publication of country-by-country financial information to help stamp out corporate tax avoidance, a survey showed on Wednesday. British lobby group the Confederation of British Industry said it still opposed the publication of country-by-country financial data.