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By: Cindy Perman, CNBC.com | 27 Apr 2009 | 05:39 PM ET
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Stocks ended lower Monday amid worries that the swine-flu outbreak could derail the economic recovery. But drug makers and pharmacies advanced.

The Dow Jones Industrial Average dropped 51.29, or 0.6 percent, to close at 8,025. The S&P 500 fell 1 percent and the Nasdaq skidded 0.9 percent.

Major U.S. Indexes
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Adding to the market's list of worries today, a Boeing 747 that is the backup to Air Force One flew low over New York's Hudson River just after 10 am ET, causing mass evacuations and panic on Wall Street and the rest of lower Manhattan. It was later revealed to be an Air Force "photo op," though one office building was told it was for an advertisement for a movie.

>> Terror Attack? No, Just Dumbest 'Photo Op' of All Time

Not surprisingly, the CBOE volatility index, widely considered the best gauge of fear in the market, climbed nearly 5 percent to nearly 39.

The threat of a flu pandemic rose after more than 100 people were confirmed to have died in Mexico from the virus and outbreaks were reported in five U.S. states, including Texas and New York, prompting the U.S to declare a health emergency. Though, no deaths were reported in the U.S.

After a man was diagnosed with Europe's first case in Spain, the EU health commissioner urged citizens to avoid any non-essential travel to the U.S. and Mexico.

That put a dent in travel-related stocks, including American Airlines [AMR  Loading...      ()   ], Carnival cruise lines [CCL  Loading...      ()   ] and Starwood Hotels [HOT  Loading...      ()   ], which all fell more than 10 percent.

And Starbucks [SBUX  Loading...      ()   ] shares fell 2.3 percent following a report that one of its employees was exposed to the swine-flu virus. The coffee chain wouldn't confirm the report, but shut down 10 cafes in Mexico City as a precaution.

>> How Flu Fears Will Crimp Spending—and Where

But some pharmaceutical stocks benefited as traders looked for the flu play.

American depositary shares of GlaxoSmithKline [GSK  Loading...      ()   ] gained 7.5 percent, as the UK drug maker, along with Switzerland's Roche were expected to be the two main beneficiaries from the need for a swine flu vaccine.

Roche gained 3.5 percent in Frankfurt.

American pharmas caught the runoff: Bristol-Myers [BMY  Loading...      ()   ] and Pfizer [PFE  Loading...      ()   ] advanced more than 2 percent.

Drug-store stocks also benefited, including Rite Aid [RAD  Loading...      ()   ], which jumped 8 percent, and CVS [CVS  Loading...      ()   ], which gained 0.6 percent.

Meanwhile, Credit Suisse downgraded its weighting on the U.S. to "market weight" from "overweight," saying American stocks are expensive relative to their peers and that earnings momentum was middling.

In earnings, Verizon [VZ  Loading...      ()   ] beat expectations, helped by its acquisition of Alltel, and its operating chief said he "has never been more optimistic about the business." But shares fell 1.5 percent.

Qualcomm [QCOM  Loading...      ()   ] rose 4.4 percent, even after the cellphone-chip maker swung to a loss, hit by investment losses and legal costs related ot its settlement with rival Broadcom [BRCM  Loading...      ()   ].

Humana [HUM  Loading...      ()   ] jumped 6.9 percent after the health insurer reported its earnings more than doubled as its government business got a boost from Medicare Advantage enrollments. The company also raised its full-year outlook.

Whirlpool [WHR  Loading...      ()   ] shot up 7.3 percent after the appliance maker reported a surprise profit as cost-cutting measures helped offset slumping sales.

Auto makers advanced after General Motors [GM  Loading...      ()   ] announced plans to cut 21,000 U.S. factory jobs by next year, phase out its Pontiac brand and offered the government GM stock in exchange for half of its debt, as part of a massive restructuring effort.

GM shares rallied 21 percent, while Ford [F  Loading...      ()   ] gained 2.2 percent.

Meanwhile, Chrysler showed signs of progress with its unionized workers on its battle to stay alive on Sunday with just days left to complete deals to slash labor and debt costs or face bankruptcy.

Bank stocks ended lower after an industry source said the stress-test results showed one bank will require additional capital.

Bank of America [BAC  Loading...      ()   ] fell 2 percent, JPMorgan [JPM  Loading...      ()   ] dropped 1.8 percent and Citigroup [C  Loading...      ()   ] lost 3.8 percent.

The first look at first-quarter gross domestic product comes out later in the week, along with a Fed meeting.

President Barack Obama's economic advisor Lawrence Summers said on Sunday that the sense of "unremitting freefall" has ended and the picture is no longer negative, but rather mixed.

World finance leaders in Washington agreed over the weekend there was a "break in the clouds" of the economic storm but said more measures were needed to ensure an end to the global recession.

A statement from the International Monetary and Financial Committee of the IMF said more action was needed to restore the health of banks and revive lending.

This Week:

TUESDAY: Two-day Fed meeting begins; Case-Shiller home-price index; Richmond Fed survey; Conference Board consumer confidence; Earnings from Pfizer, Bristol-Myers, US Steel and Sun Micro
WEDNESDAY: Weekly mortgage applications; advance Q1 GDP; weekly crude inventories; Fed rate decision; Earnings from Wyeth, Aetna, General Dynamics, Time Warner, Starbucks and Visa
THURSDAY: Weekly jobless claims; personal income/spending; Kansas City Fed report; Fed's Volcker speaks; Earnings from ExxonMobil, AstraZeneca, Cardinal Health, Colgate-Palmolive, Comcast, Ericsson, Kellogg, Motorola, Viacom and MetLife
FRIDAY: Auto sales; Fed's Geithner, Bullard speak; Reuters/Univ of Mich consumer confidence; ISM manufacturing index; factory orders; Earnings from Chevron, Clorox, MasterCard and Simon Property

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