| #5 Massachusetts |
Previous: #4 North Carolina | Next: #6 Iowa |

| Category | Score | 2010 Rank | 2009 Rank |
| Cost of Doing Business | 179 | 39 | 40 |
| Workforce | 175 | 23 | 26 |
| Quality of Life | 238 | 6 | 6 |
| Economy | 144 | 17 | 12 |
| Transportation & Infrastructure | 80 | 39 | 31 |
| Technology & Innovation | 231 | 3 | 5 |
| Education | 155 | 1 | 1 |
| Business Friendliness | 119 | 14 | 17 |
| Access to Capital | 49 | 2 | 2 |
| Cost of Living | 5 | 40 | 36 |
| OVERALL | 1375 | 5 | 8 |