European investors were set to take a wait-and-see approach to start Tuesday, with indications of little change to major markets at the opening bell.
The Federal Reserve's interest-rate decision due later in the day will likely keep many on the sidelines until they hear the latest on how Fed Chairman Ben Bernanke and company on its $600 billion program that buys securities to ease monetary policy.
Financial spreadbetters expected Britain's FTSE-100 to open 2 to 7 points lower, or as much as 0.12 percent, Germany's DAX to open 3 to 11 points lower, or as much as 0.16 percent, and France's CAC-40 to open 3 points lower to 3 points higher.
European sharesrose for a sixth straight day on Monday, the longest winning streak in five months, on optimism for the economy and with China's decision not to raise interest rates boosting miners.
The Spanish treasury aims to sell between 2 billion and 3 billion euros in 12- and 18-month bills in an auction on Tuesday which will provide an indication of the level of confidence investors have in the country.
The prospect of external help for Spain is still looming, and European leaders remain under pressure to stem the debt crisis.
German Finance Minister Wolfgang Schaeuble stressed on Monday the euro was here to stay. European leaders will defend the single currency, he said ahead of another meeting of head of state later this week.
Italian Prime Minister Silvio Berlusconi faces no-confidence votes on Tuesday which could force him from office and trigger early elections. He said on Monday a no-confidence vote risked plunging Italy into the middle of the euro zone's debt crisis.
Inflation data for France and the UK is due out on Tuesday, as are EU industrial production numbers for October and the ZEW economic think tank's monthly poll of economic sentiment in Germany.
And WikiLeaks founder Julian Assange, who was arrested in London last week, is set to appear in court on Tuesday.
-- Reuters contributed to this report