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Eric Clapton

Guitarist Eric Clapton has been one of the most popular musicians in the world since the 1960s, thanks to his work with Cream, Derek & the Dominos , and his solo career. However, his well-publicized struggles with drugs and alcohol have threatened both his career and his life on numerous occasions. In the 1970s he became a full-fledged heroin addict, and although he eventually beat that addiction, he began drinking heavily instead.

In 1982, he checked into Minnesota’s Hazelden Treatment Center. A newly sober Clapton returned to the charts with 1985’s Behind the Sun and 1986’s August, which featured the hit "It's i n t he Way That You Use It." However, in 1992 he released the single "Tears in Heaven," which peaked on the Billboard chart at number 2, and he followed it with the Unplugged album, which went to number one in the United States and has sold over 10 million copies to date, making it the best-selling album of his career.

Photo: ChinaFotoPress | Getty Images