Regardless of investors' opinion, Thiel's stock sale sends a bad message to the marketplace and raises concern about whether or not Zuckerberg knows how to run a public company, said Gordon Bethune, CNBC contributor and former CEO continental airlines.
"When you have an insider dump a large percentage of his shares, especially a board member, it sends a really bad signal, regardless whether it's warranted or not," Bethune said on CNBC's Halftime Wednesday.
And with Facebook's stock trading at about the half the IPO price, the company can't afford any "bad signals" to the market, Bethune said.
"I think he needs some help in setting expectations and making his earnings prospects so people understand what he is doing and how he is going to achieve those goals. Right now it's not clear," Bethune said.
Fiorina said while blaming Zuckerberg for Facebook's stock trouble isn't completely fair, considering the stock was "overhyped" at its IPO, it's not uncommon for founders of young companies to stunt their companies growth because they are unwilling to accept they don't have all the skill sets necessary to run a company.
"The difficulty is when a founder who has been incredibly successful up to this phase in a company's development, digs in their heels and says 'I don't need any help, I've taken us this far,' and unfortunately that happens a lot," Fiorina said on CNBC's Halftime Wednesday. "It's a little bit like saying, 'I ride a jet ski really well, therefore I can power an ocean liner.' They are totally different experiences."