On the final play of Monday night's NFL game, a controversial touchdown call changed the game's outcome.
It also reversed the Las Vegas outcome. Instead of the Packers covering the 3.5 point spread, they did not cover.
Sounds like a nuance, but in seconds, most bettors went from winners to losers and losers to winners — with some major money involved.
Some sources say it was a $150-300 million dollar swing. Various Las Vegas sources told CNBC, it was much more than that.
(Read More: For NFL, Does a Blown Call by Referees Really Matter?)
"Everyone says you should multiply Vegas betting by ten to get the overall number," said John Netto, President of Vegas-based Quantitative Sports Strategies. "But it's more like 100 times.