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  • The FDA is not obliged to follow the advice of its advisory panels but typically does so. The vote followed a skeptical presentation by FDA reviewers, who questioned the validity of the data. "FDA, please don't let me die early," urged 15- year-old Billy Ellsworth, who has the disease.

  • The vote followed an emotional meeting at a hotel in Hyattsville, Maryland, in which hundreds of patients and their advocates gathered to urge the Food and Drug Administration to approve the drug, Sarepta Therapeutics Inc's eteplirsen, saying their children had benefited from it.

  • BETHESDA, Md. _ American Capital Agency Corp. on Monday reported a loss of $772 million in its first quarter. The average estimate of six analysts surveyed by Zacks Investment Research was for earnings of 57 cents per share. American Capital Agency shares have climbed nearly 8 percent since the beginning of the year.

  • But beyond the chart-toppers and dance parties, the legacy of Prince Rogers Nelson grew to include political stances, challenges to record execs and an overarching focus on African-American empowerment. At the Grammys in Los Angeles, Prince was referring to the Black Lives Matter Movement that was galvanized by the 2014 police killing of an unarmed Michael...

  • BETHLEHEM, Pa., April 24- With a rusting steel mill in its center, this Pennsylvania city would seem fertile ground for Donald Trump's campaign and its vision of a declining America that only he can fix. Bethlehem and the Lehigh Valley region around it have filled new industrial parks with e-commerce companies, white collar businesses fleeing New York's high...

  • ELLICOTT CITY, Md. _ Howard Bancorp Inc. on Friday reported net income of $960,000 in its first quarter. Howard Bancorp shares have decreased 7.5 percent since the beginning of the year. Keywords: Howard Bancorp, Earnings Report.

  • BETHESDA, Md. _ LaSalle Hotel Properties on Thursday reported a key measure of profitability in its first quarter. The average estimate of 11 analysts surveyed by Zacks Investment Research was for funds from operations of 44 cents per share. Eight analysts surveyed by Zacks expected $262.5 million.

  • EASTON, Md. _ Shore Bancshares Inc. on Thursday reported first-quarter profit of $2.5 million. Shore Bancshares shares have risen 10 percent since the beginning of the year. Keywords: Shore Bancshares, Earnings Report.

  • OLNEY, Md. _ Sandy Spring Bancorp Inc. on Thursday reported first-quarter net income of $10.8 million. The average estimate of four analysts surveyed by Zacks Investment Research was also for earnings of 45 cents per share. Sandy Spring Bancorp shares have increased 5.5 percent since the beginning of the year.

  • BALTIMORE— Under Armour Inc. on Thursday reported first-quarter profit of $19.2 million. Under Armour expects full-year revenue of $5 billion. Under Armour shares have risen 5.5 percent since the beginning of the year, while the Standard& Poor's 500 index has risen almost 3 percent.

  • BETHESDA, Md. _ Eagle Bancorp Inc. on Wednesday reported first-quarter net income of $23.3 million. Eagle Bancorp shares have decreased slightly more than 1 percent since the beginning of the year. Keywords: Eagle Bancorp, Earnings Report.

  • Also nominated as finalists: InsideClimate News, for a report that Exxon conducted climate research and then, without revealing the information to its stockholders, worked to cast doubt on the scientific consensus it confirmed; and the Tampa Bay Times, for a story on education in Pinellas County, Florida. Leonora LaPeter Anton and Anthony Cormier, of the Tampa...

  • Post-NY campaign trail

    CNBC's Eamon Javers looks at the road ahead for both parties in the race to the White House following the primary in New York.

  • WASHINGTON— Short of savings and burdened by debt, America's millennials are struggling to afford their first homes in the face of sharply higher prices in many of the most desirable cities. Steadily rising home values in recent years have eclipsed pay increases, making it especially difficult to buy in major growth areas for jobs, such as San Francisco, Denver...

  • WASHINGTON— Congress seems increasingly unlikely to take action to help Puerto Rico ahead of a May 1 deadline for the commonwealth to default on a nearly half-billion-dollar debt payment. The blown deadline could push Puerto Rico and its 3.5 million American citizens further into crisis, exacerbating a growing fiscal and humanitarian disaster that's been...

  • WASHINGTON, April 19- The U.S. Supreme Court on Tuesday ruled against Maryland in its bid to revive a program to subsidize natural gas-fired electricity plant construction to serve the power needs of its residents in a case weighing state versus federal authority. Writing on behalf of the court in the 8-0 ruling, liberal Justice Ruth Bader Ginsburg said the...

  • WASHINGTON— A unanimous Supreme Court ruled Tuesday that Maryland officials overstepped their authority when they offered financial subsidies to encourage construction of a new power plant in the state. The justices said the Maryland plan interferes with federal law governing wholesale electricity rates. The ruling is a setback for Maryland and other...

  • WASHINGTON, April 19- The U.S. Supreme Court on Tuesday ruled against Maryland in its bid to revive a program to subsidize natural gas-fired electricity plant construction to serve the power needs of its residents in a case weighing state versus federal authority.

  • Also nominated as finalists: InsideClimate News, for a report that Exxon conducted climate research and then, without revealing the information to its stockholders, worked to cast doubt on the scientific consensus it confirmed; and the Tampa Bay Times, for a story that studied the effects on education in Pinellas County, Florida. Leonora LaPeter Anton and...

  • The filing deadline on Monday was delayed three days beyond the traditional April 15 deadline because Friday was a legal holiday in the District of Columbia. The traditional April 15 filing deadline was extended because of Emancipation Day, a legal holiday in the nation's capital. In Massachusetts and Maine, taxpayers get one more day to file.