Theresa May triggered the pound's biggest jump in eight years.
Gains were capped by forecasts for rising U.S. and Russian production and skepticism that OPEC as a whole would comply with output cuts.
Gold jumped to its highest in nearly eight weeks on Tuesday after U.S. President-elect Donald Trump said the dollar was "too strong."
U.S. stock index futures pointed to a lower open on Tuesday as investors digested key remarks from the top British leader.
Asia shares traded mixed on Tuesday, with Japanese stocks under pressure from a relatively stronger yen.
European stocks closed lower on Monday as investors await more detail on the U.K.'s Brexit plan and eyed Trump's inauguration on Friday.
Samsung shares slumped on Monday after news that a South Korean special prosecutor will seek an arrest warrant for the Samsung Group chief.
Sterling was hit by fears that Prime Minister Theresa May will say on Tuesday that Britain will lose its access to the EU single market.
Oil was pressured by doubts that large oil producers will reduce production and on expectations that U.S. production would increase.
Gold prices rose on Monday, supported by safe-haven demand due to uncertainty over U.S. policy.
Stocks closed mostly higher, boosted by strong quarterly earnings from banks, while investors also digested several pieces of economic data.
U.S. government debt prices fell on Friday, as investors digested key economic data.
European markets closed higher on Friday as investors digested better-than-expected corporate earnings from the U.S.
Asian markets fell on Friday, as investors digested China's full-year trade figures in yuan-terms and waited for more data to be released.
The U.S. dollar gained against the yen and was little changed against the euro on Friday, rebounding from five-week lows.
Oil prices fell on lingering doubts over the extent of OPEC cuts, with sentiment worsened by concerns over the economic health of China.
The price of gold eased on Friday from a 7 week high touched in the previous session after strong U.S. retail sales.
Stocks fell on Thursday after President-elect Donald Trump disappointed investors during his first news conference since July.
U.S. stock index futures pointed to a flat open on Friday as traders digested some big earnings reports and economic data.
U.S. government debt prices were higher on Thursday as investors continued to digest President-elect Donald Trump's latest remarks.