European stocks were mostly higher following polls that allayed fears of a Brexit, however, a decline in oil prices added pressure to sentiment.
Japanese markets on Tuesday reversed early losses of as much as 1.13 percent to trade higher as rest of Asia close mixed.
Sterling and the euro rose on the last day before Britain's referendum on EU membership, the pound trading just off its highest this year.
Gold fell for a second session in a row on Tuesday as fears that Britain could vote to leave the European Union in Thursday's referendum receded.
Oil prices reversed their losses in post-settlement trade after API data showed a bigger-than-expected draw on inventory.
U.S. stocks closed higher Monday, amid gains in oil prices, as fears of a Brexit diminished.
European stocks surged by Monday's close, as declining fears of a Brexit vote buoyed global market sentiment, sterling and oil prices.
The Treasury Department auctioned $26 billion in two-year notes at a high yield of 0.745 percent on Monday.
Asia markets closed higher on Monday, after U.K. polls gave the remain camp a slight edge ahead of the June 23 Brexit referendum.
The dollar tumbled on as sterling surged more than 2 percent and the euro jumped after opinion polls swung in favor of remain.
Gold fell on Monday after polls showed the campaign for Britain to remain in the European Union regaining some momentum.
Oil rose, lifted by a wave of investor confidence and a weaker dollar after polls showed a smaller chance of Britain voting to leave the EU.
U.S. futures were indicating another positive start for major Wall Street indexes Tuesday as Brexit fears faded amid fresh polls.
U.S. stock index futures indicated a higher open Monday as global markets rallied on Brexit polls that showed the remain camp making gains.
U.S. stocks closed lower Friday, with health care and tech stocks lagging, amid continued uncertainty ahead of next week's scheduled Brexit vote.
U.S. government debt prices were mixed as investors digested better-than-expected housing data.
European markets opened higher on Friday, on the back of a positive trading session in Asia and a tick-up in oil prices.
Asia's markets closed higher on the final day of a volatile week amid easing concerns that the U.K. would vote to exit the EU in its June 23 referendum.
Sterling rose as traders evaluated whether the killing of MP Jo Cox may alter the balance of opinion on Brexit.
Gold rose more than 1 percent on Friday, supported by a softer dollar and cautious interest rate comments.