Most Asian markets dropped more than 1 percent, after a poll showed the GOP's Donald Trump leading rival Hillary Clinton.
Gold prices briefly hit highest level at $1309.10 an ounce for the first time since October 4th.
U.S. stock index futures pointed to a lower open on Wednesday, as investors prepared for more earnings, while awaiting the latest Fed decision.
U.S. equities fell as recent election news and a Fed meeting sent jitters through the market.
U.S. government debt prices whipsawed on Tuesday, amid uncertainty surrounding the U.S. election.
European shares closed lower on Tuesday with investors focused on another batch of earnings reports as well as the Fed rate decision.
The dollar hit lows Tuesday on U.S. political uncertainty, while the peso hit a low on positioning for a potential victory for Trump.
A weak dollar boosted greenback-denominated commodities, but worries that OPEC cannot reduce a global glut kept oil prices near one-month lows.
Investors awaited cues from a series of upcoming central bank policy meetings and U.S. economic data.
U.S. stock index futures pointed to a flat to slightly higher open, as investors prepared for further earnings and more election news.
Chinese markets traded higher after stronger-than-expected twin PMI surveys gave investors a boost of confidence.
The Dow and S&P extended their slide to three months, while the Nasdaq snapped a three-month winning streak.
U.S. government debt prices were slightly higher on Monday as investors digested the latest news surrounding the U.S. election and the Fed.
European markets closed lower Monday as revelations over the weekend increased uncertainty over the upcoming U.S. presidential election.
The dollar rose Monday on reduced worries over the FBI's investigation of more emails linked to Clinton's use of a private server.
Oil prices slid on Monday after non-OPEC producers made no specific commitment to join OPEC in limiting oil output levels to prop up prices.
But, concerns over the outlook for the U.S. election and Federal Reserve policy kept the metal pinned near its three-week high.
Asian markets traded lower, as worries about the U.S. presidential election, weak Japan data and lower oil prices weighed on sentiment.
U.S. stock index futures pointed to a slightly higher open, amid uncertainty surrounding the U.S. election and what the Fed might do next.
Stocks closed mostly lower after the FBI announced it is investigating new emails related to Democratic nominee Hillary Clinton.