Caution Advised for High-Risk Patients Using Celebrex


Doctors should prescribe the lowest doses of Celebrex possible in patients at high risk of heart problems, researchers who did a combined analysis of six studies of the Pfizer pain drug said on Monday.

The analysis suggests that the potentially harmful effect of Celebrex dosage is most pronounced in higher-risk patients, researchers said at the American College of Cardiology scientific meeting.

"These data should provide some measure of comfort in prescribing celecoxib to patients with very low cardiovascular risk," said Dr. Scott Solomon, lead researcher of the National Cancer Institute-sponsored study, using the generic name for Celebrex.