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Pops & Drops: Quest Diagnostics, Sears...

Following are the day’s biggest winners and losers. Find out why shares of Quest Diagnostics and Jeffries Group popped while Sears and National City dropped.

POPS (stocks that jumped higher)

Quest Diagnostics (DGX) popped 8%. The medical test company said profits were up 32% due in part to its AmeriPath acquisition. – I like the space, says Pete Najarian.

Stock Pops & Drops

Jeffries Group (JEF) popped 1%. This stock surged 15% mid morning on word the firm secured a capital infusion from Leucadia National Corp – however by the close shares drifted back to earth. – They used the money to buy shares of Leucadia, explains Karen Finerman.

Danica Patrick.
Danica Patrick became the first ever female winner in IndyCar racing, coming in First Place in the Indy Japan 300.

Western Union (WU) popped 3%. The money transfer giant jumped ahead of Tuesday's earnings. – Sell the news, exclaims Jeff Macke.

Hess (HES) popped 7%. Oil's march to $117 took Hess along for the ride. – They’re more than a refiner, explains Pete Najarian.

Pilgrim's Pride (PPC) popped 9%. Credit Suisse analysts said rising poultry prices should benefit the world's largest chicken producer.

DROPS (stocks that slid lower)

National City Corp. (NCC) dropped 28%. The Cleveland-based bank slashed its dividend from 21-cents to a penny, and sold a $7 billion stake to an investor group at a 40% discount. – Stay away, counsels Karen Finerman.

Sears Holding (SHLD) dropped 7%. Bank of America refused to renew a $1 billion letter of credit for America’s retail giant. – Tough times for Sears, says Jeff Macke.

Eaton Corp. (ETN) dropped 3%. The hydraulics company considered selling 17.5 million shares to pay down debt. – I like this stock as an early cycle name, says Guy Adami.

Amylin Pharmaceuticals (AMLN) dropped 10%. Lackluster sales of Byetta and other drugs disappointed investors. – I think it’s a buy on this pullback, says Pete Najarian.

China Mobile (CHL) dropped 2%. Although profits were up 37% for the quarter, investors sold the stock off for no clear reason. – I think it’s people taking profits, explains Guy Adami.

Thornburg Mortgage (TMA) dropped 3%. A subsidiary of the beleaguered home-loan company defaulted on $300 million worth of short-term notes. – It was only a 4 cent move, says Karen Finerman.

Centex (CTX) dropped 4%. Homebuilder shares slumped ahead of earnings. – If you want to play the space I prefer HD, counsels Guy Adami.

James Bond's Car. A stunt driver on the upcoming Bond film "Quantum of Solace" accidentally drove 007's car, an Aston Marten DBS, into Lake Garda in northern Italy. The driver emerged with only minor bruises.

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Trader disclosure: On Apr. 21, 2008, the following stocks and commodities mentioned or intended to be mentioned on CNBC’s Fast Money were owned by the Fast Money traders; Macke Owns (DIS), (YHOO), (MSFT), (HAS), (INTC); Najarian Owns (AAPL), (XLF), (YHOO), (UA) (NOK); Najarian Owns (BHI) Calls, (CHK) Calls, (MSFT) Calls, (RSH) Calls, (POT) Calls, (ICO) Calls; Finerman Owns (GS); Finerman's Firm And Finerman Own (MSFT); Finerman's Firm Owns (SUN), (TSO), (VLO), (WMT), (YHOO), (BJS); Finerman's Firm Is Short (IYR), (IJR), (MDY), (SPY), (IWM); Finerman's Firm Owns Shares Of Expro International Group PLC; Finerman's Firm Is Short Pounds; GE Is The Parent Company Of CNBC; NBC Universal Is The Parent Company Of CNBC; Charles Schwab Is A Sponsor Of "Fast Money"