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10. Ghost (1990)

Return on investment: 1446%
Budget: $35 million (inflation-adjusted)
Gross Revenue: $506 million

1990’s Ghost starred Patrick Swayze as a yuppie who lives with Demi Moore, who has a passion for making pottery. When he’s murdered in a robbery attempt, his ghost enlists the help of a medium played by Whoopi Goldberg in order to find out why he was killed.

The movie was made on a modest budget, but the love story at its center resonated profoundly with audiences who went back to see the film again and again. The movie went on to become the highest-grossing film of 1990, and earned almost $506 million, over fourteen times its cost.

Photo: Paramount Pictures