Retired schoolteacher Donald Hovasse signed up for Twitter about a year ago at the urging of his daughter. He lost interest after trying the service a few times and finding lots of celebrities but few of his friends using the online social network.
"I didn't really get the point of it at all," said the Las Vegas resident. "Most of them were people I wasn't interested in hearing what they had to say anyway." He said, however, that he does check Facebook every day to see what his friends are up to.
Hovasse's experience highlights a risk for investors as Twitter mfaarches towards this year's most anticipated initial public offering in the United States, expected to begin trading on the New York Stock Exchange in mid-November.
According to a Reuters/Ipsos poll, 36 percent of 1,067 people who have joined Twitter say they do not use it, and 7 percent say they have shut their account. The online survey, conducted Oct. 11 to 18, has a credibility interval, a measure of its accuracy, of plus or minus 3.4 percentage points.
(Read more: Twitter squeezes underwriters on IPO: Reports)
In comparison, only 7 percent of 2,449 Facebook members report not using the online social network, and 5 percent say they have shut down their account. The results have a credibility interval of 2.3 percent.
People who have given up on Twitter cite a variety of reasons, from lack of friends on the service to difficulty understanding how to use it. Twitter declined to comment for this story, saying it is in a quiet period ahead of its IPO.
Twitter's attrition rate highlights a challenge that has dogged the online messaging site over the years: while it has managed to enlist many high-profile and avid users, from the Pope to President Barack Obama, Twitter has yet to go truly mainstream in the way Facebook has.
Convincing ordinary people to think of Twitter as an indispensable part of their lives is key to the company's ability to attract advertisers and generate a profit.
Twitter reported it had 232 million "active" users - people who access the service at least once a month - at the end of September, up 6.1 percent from the end of June. Twitter's quarter-over-quarter growth in active users has not exceeded 11 percent since June 2012.
When Facebook was a similar size, its active users were increasing by more than 20 percent every quarter, and it was not until the social network neared the half-a-billion member mark that its user growth decelerated to 12 percent.
"Twitter is a great service, it's still got growth in front of it. But in my opinion, I would say the opportunities are less than that of Facebook, and it has to be valued appropriately," said Dan Niles, chief investment officer of tech-focused hedge fund firm AlphaOne Capital Partners.
"The data would seem to imply that the ultimate revenue potential for this company is less than for Facebook," Niles said, referring to Twitter's number of active users.
Twitter's revenue in the third quarter more than doubled from the year before to $168.6 million, while its net loss tripled to $64.6 million. Analysts expect Facebook, which is due to report its third-quarter results later this month, to bring in $1.9 billion in quarterly revenue.
Twitter aims to become the "fabric of every communication in the world" and to eventually reach every person on the planet, Chief Executive Dick Costolo has said. Still, Twitter acknowledged in its IPO prospectus that "new users may initially find our product confusing."
The company prides itself on staying true to its roots: it lets people send 140-character messages and does not pack in scads of extraneous functions. Since its inception, Twitter has resisted overtly manipulating how people use its platform, instead preferring conventions to be formed organically.
As a result, new users often find it initially difficult to grasp how discussions ebb and flow, complaining that features such as the "hashtags" that group Tweets by topic, abbreviations for basic functions (for instance, RT for retweet) and shortened Web links, are geared towards a technologically-savvy crowd.
"The average person that's coming on here, they're still baffled by it," said Larry Cornett, a former executive at Yahoo and designer at Apple, who now runs product strategy and design consulting firm Brilliant Forge.
"If they want the mass adoption and that daily engagement, they have to make it really easy for people to consume."