Analysts say the partial U.S.-China trade deal doesn't touch on thorny issues plaguing both sides, and warn talks could break down again.World Economyread more
Economists polled by Reuters had expected Chinese exports denominated in the U.S. dollar to fall by 3% and imports to decline by 5.2% in September, compared to a year ago.China Economyread more
The U.S. had plans to hike duties on at least $250 billion in Chinese goods to 30% from 25% on Tuesday. Despite the partial trade deal, some banks on Sunday wrote that tariff...Marketsread more
The industry has pulled in $322 billion over the past six months, the fastest pace since the second half of 2008.Marketsread more
A technical recession occurs when there are two consecutive quarters of economic contraction.Asia Economyread more
"Deepfakes" are being used to depict people in fake videos they did not actually appear in, and can potentially affect elections, diplomacy and how markets move, experts say.Technologyread more
Chinese President Xi Jinping warned on Sunday that any attempt to divide China will be crushed.China Politicsread more
Syria's Kurds said Syrian government forces agreed Sunday to help them fend off Turkey's invasion.World Newsread more
U.S. President Donald Trump said that both sides reached a "very substantial phase one deal" that will address intellectual property and financial services concerns and...Asia Marketsread more
Hagibis dropped record amounts of rain for a period in some spots, according to meteorological officials, causing more than 20 rivers to overflow.Asia Newsread more
A spokesperson for the U.S.-backed Syrian Democratic Forces (SDF) has issued a stark warning to the international community.World Newsread more
An experimental GlaxoSmithKline drug, designed to fight heart disease in a new way, failed to meet its main goal in a major late-stage clinical study, dealing a blow to one of the company's biggest new treatment hopes.
Darapladib's inability to reduce the risk of heart attacks and strokes in the first of two big Phase III clinical studies is disappointing, but not a huge surprise. Many analysts already had low expectations for the project.
The once-daily pill did produce greater reductions in serious coronary events in some of the pre-defined secondary end points of the trial, which GSK said required more analysis.
(Read more: GSK's China sales topple on bribery scandal)
Darapladib is designed to prevent heart attacks and strokes in a completely different way from cholesterol-lowering drugs by targeting an enzyme called Lp-PLA2 that is linked to artery-clogging plaques.
While some industry analysts have suggested it could become a $10 billion-a-year seller, if it works, few have pencilled insignificant sales forecasts so far, given uncertainty about the product.
Current consensus forecasts point to annual sales of only $605 million in 2018, according to Thomson Reuters Pharma.
(Read more: Hearts beating disease)
Patrick Vallance, GSK's head of pharmaceuticals R&D, said Britain's biggest drugmaker would continue to investigate the role of Lp-PLA2 inhibition in coronary heart disease and other conditions, while also poring over the latest trial results.
"We will now work to better understand the data, including evaluation of the patient sub-groups, and await the outcome of a second Phase III study of darapladib in acute coronary syndrome," he said.
The first trial, known as STABILITY, enrolled nearly 16,000 patients with coronary heart disease in 39 countries and measured the differences in outcomes between giving them darapladib or a placebo pill.
A second 13,000-patient study, called SOLID-TIMI 52, is due to complete in March 2014 and is looking at patients who have already suffered an acute coronary event. It will assess if darapladib can prevent a secondary attack.
Some medical experts believe darapladib may have a better chance of success in the second study.
GSK has had some notable successes with its new drugs this year, including approvals of new medicines for cancer, lung disease and HIV. But it also had disappointing clinical results with another high-risk product in September, its MAGE-A3 cancer vaccine for melanoma.