Spanish media say Mexican businessman Miguel Valladares is likely to come to the rescue of entertainment firm Zinkia, producer of the internationally-known cartoon Pocoyo, which recently filed for insolvency.
They also predict a deeper partnership between billionaire Carlos Slim and lender La Caixa, which along with other Spanish savings banks is considering the sale of vast corporate stake holdings to meet stricter European capital rules.
Slim still heads the list of Mexican billionaires,13 of whom figured in the top 1,000 of Forbes Magazine's annual rich list at the start of 2013, with a total net worth of almost $146 billion.
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By comparison, there were 11 Spaniards with assets valued at nearly $90 billion.
Mexican Economy Minister Ildefonso Guajardo said the financial crisis had created opportunities for investors in Europe at a time when Mexican companies were already looking to expand their reach into the rest of the world.
"Before, we only looked at attracting investment. Today Mexico is making record foreign investments," he told Reuters.
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Lured by a more stable legal and investment framework in Europe versus Latin America, large fortunes and family offices are using Spain as an entry point to the Old Continent.
The strong presence of Spanish banks such as BBVA and Santander in Latin America has also helped facilitate business.
"The trend is a reverse from what was seen 10-15 years ago when Spanish firms invested heavily in Mexico acquiring local banks and participating in bids to build major infrastructure projects,"said Jim Seale, president of Seale & Associates, which is currently advising a Mexican firm looking to buy in Spain.