Take a look at some of Wednesday's midday movers:
Harley-Davidson shares hit a bump in the road after Raymond James downgraded the motorcycle maker to "market perform" from "strong buy," citing its own survey that indicated sales during the second quarter fell below growth estimates.
GoPro shares fell after doubling in value from its initial offering price last week.
Greenbrier shares rose on news that the maker of railroad cars raised its full-year earnings forecast after reporting better-than-expected profits in the third quarter. The revised forecast comes after increased railcar deliveries.
WebMD shares gained ground after Stifel Nicolaus raised its rating on the health information provider to "buy" from "hold" with a $60 price target, saying current estimates for advertising growth at the end of the year are conservative.
St June Medical shares moved higher on news the FDA notified the company that manufacturing issues at its California plant had been resolved.
Shutterfly soared on a Bloomberg report that the online photo-printing service has put itself up for sale.
Insys Therapeutics climbed after the FDA granted the company's epilepsy drug the designation of orphan drug, which gives it a seven-year period of market exclusivity in the United States.
McDonald's moved lower after a Consumer Reports survey said the fast food chain offered the .
Destination Maternity moved higher on reports the maternity clothes retailer will continue to pursue Britain's similar retailer, Mothercare, after saying that it had two bid proposals rejected.
—By CNBC's Rich Fisherman.