Shanghai down 0.6%
China's benchmark Shanghai Composite extended losses into a second day, retreating further from a one-month high of 2,075 points touched on Wednesday's session.
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Property developers fell ahead of the release of June home price data on Friday. China Vanke and China Merchants Property fell over 1 percent each.
In Hong Kong, casino Sands China fell over 1 percent after Las Vegas Sands reported weaker-than-expected earnings in U.S. trade.
Japanese shares erased gains after climbing to fresh one-and-a-half-week highs earlier in the day, extending losses into a second day.
Sumitomo Electric Industries rallied 1.1 percent after U.S. manufacturer 3M said it would buy pay about $885 million for Sumitomo's stake in their Japanese joint venture.
Air bag manufacturer Takata fell over 4 percent after BMW said it would recall 1.6 million cars worldwide to replace the Japanese company's faulty air bags.