The Conservatives, who have ruled in coalition with the more left-wing Liberal Democrats since 2010, are rated by voters much more highly than the opposition Labour party on the economy. But they lag narrowly behind Labour in opinion polls less than eight months before the election.
Osborne has focused on bringing down Britain's massive budget deficit since he took over the finance ministry in 2010. But with the public accounts still deep in the red, he has little room to offer major tax cuts ahead of the election.
Last week, Labour promised to levy new taxes on homes worth more than 2 million pounds ($3.3 million) and on tobacco firms in order to pump cash into healthcare if it wins the election.
Britain's economy has staged a much stronger-than-expected recovery since mid-2013 and Osborne, in his speech on Monday, will seek to remind voters that keeping the economy growing will be vital to create jobs, build more houses, fund healthcare and raise living standards.
Read MoreUK minimum wage hike won't hurt jobs: Labour
Osborne has long sought to remind voters that Labour was in power during the 2007-08 financial crisis that plunged Britain into its deepest post-war recession.
Osborne says the increasingly left-wing ideas of Labour leader Ed Miliband threaten the push to eliminate the budget deficit before the end of the decade.
"The idea that you can raise living standards, or fund the brilliant NHS (National Health Service) we want, or provide for our national security without a plan to fix the economy is nonsense," Osborne said.
Last week, Miliband gave a conference speech in which he forgot to mention the budget deficit. Labour's would-be finance minister Ed Balls has said the party will tackle the deficit with a plan that is less aggressive than Osborne's.