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Yet, there is a nervousness around the jobs report, after a choppy week in the equity market, and fears that Europe's weakness and China's uncertain growth rate could weigh on the U.S. economy. Stocks Thursday were little changed after Wednesday's selloff. The S&P 500 was barely changed at 1,946, and the Dow was down 3 points to 16,801, while the Nasdaq was up 8 points at 4,430. The small-cap Russell 2000, which fell into correction territory Wednesday rose 1 percent to 1,096
"I expect 220,000 and no change in unemployment at 6.1 percent," said Mark Zandi, chief economist for Moody's Analytics. "I think we'll probably get 25,000 on the upward revision this month and another 25,000 next month."
He said everything points to the fact the economy has been creating roughly 200,000 jobs for the past eight months, despite the blip in August.
Zandi said it would be a negative for market psyche if the number misses.
"It doesn't mean anything's changed but given the dark feelings out there, it will exacerbate those feelings," he said. "We've got a lot of weakish numbers coming out of the rest of the world, making people nervous. China's growth rate, Europe's gone flat again, a lot of the emerging markets are struggling to regain their footing…We're relying on the U.S. to be the engine of growth so if you have a weak jobs number, with no revision, it would fuel those concerns."
Read MoreUS stocks end little moved before jobs report
Wells Fargo chief economist John Silvia expects to see 205,000 jobs and a revision to the prior month. "If you don't have the revisions and you have a number like 205,000, it definitely flags," he said. Silvia said economists would begin to reassess expectations for 3 percent GDP growth, if the jobs number were disappointing. He said he is concerned by the unexpected drop in consumer confidence to 86 in September from 92.4 in August.
Economists say a miss in payrolls would not change the course for the Fed at its October meeting, where it is expected to announce the final tapering of quantitative easing. But a recurring trend of weakness would become an issue as it heads toward rate hikes, mostly expected to begin in mid-2015.
"There's more risk of pushing the Fed back than bringing the Fed forward at this stage of the game," said David Ader, CRT Capital chief Treasury strategist. He said if the jobs number disappoints, expect more buying in the belly of the Treasury curve—notably the five-year note—since it reflects short-term interest rate expectations.
However, economists say the trend in weekly jobless claims, which fell to 287,000 last week from the previous week's 295,000, is a positive sign for job creation.
"If the job market were weakening, you'd see jobless claims rising, not falling. They're as good as any indicator and they're not telling us the labor market is slowing," said Deutsche Bank chief U.S. economist Joseph LaVorgna.
LaVorgna expects 200,000 nonfarm payrolls. LaVorgna said one clue to September's number is that tax receipts rose a strong 5.5 percent for the month. He does expect hours worked to stay flat, and he notes the jobs report in the last two Septembers was relatively weak but there was a snapback both years in October and November.