A key forward indicator of economic health, euro zone PMI figures, released last week, suggested that Italy, along with France, remains the weak spot of the euro zone. The IMF expects Italy's economy, as measured by gross domestic product, to shrink by 0.2 percent this year.
The vote of confidence is likely to be passed, if only because even sceptics within the Renzi-led coalition don't want yet another government to fail.
Yet the undermining of Renzi is likely to continue.
"Renzi formed a cabinet in order to be the only star. He has people with good will, but no experience, except for the economy minister (Pier Padoan)," Lucio Malan, a senator from the opposition Forza Italia-PdL party and prominent supporter of former Prime Minister Silvio Berlusconi, told CNBC.
- By CNBC's Catherine Boyle.