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We all deserve a break, and Jim Cramer is looking for signals in the market to create an end to the selling. The bear markets were out on the prowl Friday in markets such as minerals, oil and gas, and even semiconductors.
U.S. stocks fell on Friday, with the Dow ending in negative territory for the year and the S&P 500 posting its worst week since May 2012. The Dow Jones industrial average (.DJI) fell 115.15 points, or 0.69 percent, and the (.SPX) lost 22.08 points, or 1.15 percent.
This market is pure treachery, Cramer said. In the event that more is to come, he is arming investors with his guide to working the market next week.
Wednesday will feature the cult of Netflix (NFLX). "This market's become badly bifurcated between those companies that have captured America's fancy—think Netflix, Amazon (AMZN) and Tesla (TSLA)—and then the rest of the companies which actually have to show earnings, not just exciting press releases when they report, " Cramer added.
Read MoreCramer's gameplan: The hopeful bull
There was some headwind in the news on the economy on Friday, with Chinese Premier Li Keqiang saying on a visit to Germany on Friday, that the global economy was facing more uncertainty but that China still had "vast growth potential."
Likewise, German Chancellor Angela Merkel expressed willingness to take actions necessary to stimulate growth. The "Mad Money" host is happy that they finally acknowledged the elephant in the room.
Cramer thinks this is a step in the right direction and that it's better late than never.
Exploring the economy's condition, Cramer shared his worst case scenario on the oil market: That it could be sowing its own seeds of demise with the Permian Basin.
In the current state of the oil and gas industry, the Bakken in North Dakota is producing an awesome 1.1 million barrels a day. The Eagle Ford region is producing 1.5 a whopping million barrels a day. But the Permian upstages them all and is producing an amazing 1.7 million barrels: which could double in the next two years.
"Think about it. We have no energy policy. We don't have a fossil fuel friendly president who sees what is about to happen: overproduction with no place to put the oil," Cramer added.
Cramer then turned his attention to a sector that has no sensitivity to the mess in Europe or economy of China, pharmaceuticals. He spoke with the chairman and CEO of ISIS Pharmaceuticals (ISIS), Stanley Crooke.
Cramer thinks that ISIS Pharmaceuticals is a game changer, as they specialize in drugs that cure rare diseases, specifically, in anti-sense technology. So, if someone has a genetic disorder, the company's platform may have a resolution.
What Cramer likes about ISIS Pharmaceuticals is that they have so much in the pipeline—32 drugs to be specific, most importantly a treatment for spinal muscular atrophy.
The stock Initially jumped 4 percent Friday on the positive muscular atrophy results, but then pulled back hard to close down 2 percent. However, Cramer has seen this stock climb as he has watched it.
"The reason we have grown so fast is that we have made observations that were so much more optimistic than what we hoped… We are seeing things that encourage us. But we still have to prove our value," said Crooke.
All eyes were on the Lightning Round on Friday, to hear Cramer's thoughts on stocks to spot the market bottom.
FMC Corp (FMC): "This is a company that is involved with agriculture. And if it's involved with agriculture, it is going lower."
Expedia (EXPE): "Expedia is related to travel. Right now we are in the grips of a fear, perhaps irrational, of Ebola. If there are negatives about Ebola that come out within the next 10 days, than Expedia is going to go lower. That's too high of a risk for a stock on this market. I don't want to buy."