Take a look at some of Tuesday's midday movers:
Amgen - The drug developer slid after its experimental ovarian cancer drug failed to improve overall survival rates in a late-stage trial.
Burger King Worldwide - The fast-food chain declined after reporting a quarterly loss.
Capital One Financial - The lender fell after disclosing a probe by the New York district attorney's office into its subprime auto-finance practices.
Estee Lauder Cos - The cosmetics company dropped after cutting its full-year profit and sales outlook.
Foot Locker - The sneaker chain moved lower after saying Chief Executive Officer Ken Hicks would retire on Dec. 1.
Ford Motor - The automaker edged lower after recalling 202,241 vehicles.
Mack-Cali Realty - The real estate investment trust rose after saying CEO Mitchell Hersh would step down in May.
Motorola Solutions - The maker of radio systems gained as it hiked its share buyback authorization by $5 billion.
Texas Roadhouse - The restaurant chain climbed after posting quarterly revenue that beat estimates.
Vitamin Shoppe - The seller of nutritional supplements fell after posting weaker-than-expected third-quarter results.
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