There are just 16 labels left in CNBC's Most Loved Label contest, and voting in each round will be growing shorter, with voting lasting just 24 hours.
If we learned anything in Round Two, it's that every vote matters for these beer brands. That's the lesson learned in the South Region, anyway, after Parkway Brewing's Majestic Mullet edged Foothills Brewing Sexual Chocolate by one vote, 598 to 597.
Read MoreCast your vote for your favorite beer labels here.
Parkway will now meet Karbach Brewing's Yule Shoot Your Eye Out, which has received the most votes in total in the South Region thus far. The other side of the bracket will pit Lone Pint's Yellow Rose versus the surfing turtle from Terrapin.
The other thing we know after two rounds is that Deschutes Brewery is putting the squeeze on its opponents. The Fresh Squeeze label for its IPA has dominated in its first two match-ups, winning by more than 1,600 votes combined. Deschutes looks to get its first real test in Round Three as it meets 21st Amendment's Sneak Attack.
The other big vote getter in the Pacific region has been Beachwood Brewing's Tovarish, which has taken down two larger competitors in Rogue Ales and Redhook Brewery. Beechwood will now face off against another Pacific Region Goliath in Stone Brewing Co., which bested fellow heavyweight Sierra Nevada in a tight contest.
After an impressive debut in Round One in the Central and Mountain Region, Black Box Brewing ran out of steam, losing handily to Odell Brewing's Lugene. Odell's cow-inspired label fell just short of another 1,000-vote round. Odell will square off against Founders Brewing Dark Penance in Round Three. Founders has posted two solid rounds and narrowly beat out Tallgrass Brewing's 8-Bit label.
Read MoreCNBC's most loved label: A gallery of contestants
The other matchup in the Central and Mountain Region will pit two labels that have both gotten off to solid starts. Left Hand Brewery's Good JuJu will meet Uinta Brewing. Both breweries have posted similar numbers in each round, and this matchup could be a close one.
Newburgh Brewing and its label featuring Betsy the cow is off to big start in the East Region, with Newburgh posting more than 1,000 votes in each of the first two rounds. Newburgh will face Victory Brewing's Dirt Wolf in what should be a tight contest. Meanwhile, Dogfish Head Craft Brewery's artistic Punkin Ale continues to advance. Dogfish will meet Long Trail Limbo, which beat sister brewery Otter Creek in Round Two.