Masitinib in Amyotrophic Lateral Sclerosis - current status and perspectives
11 May 2015 (5.35pm - 6.35pm CET)
Paris, France, April 29, 2015 (GLOBE NEWSWIRE) -- AB Science SA (NYSE Euronext - FR0010557264 - AB), a pharmaceutical company specializing in the research, development and commercialization of protein kinase inhibitors (PKIs), is hosting a web conference on masitinib in the treatment of amyotrophic lateral sclerosis (ALS) with key opinion leaders from this disease.
The web conference call will be held on 11 May 2015 from 5.35pm to 6.35pm CET.
The web conference will provide the opportunity to understand:
- The current positioning of masitinib in ALS
- The scientific rationale for developing masitinib in ALS
- The efficacy and safety update on the on-going phase 3 study
- The market potential for masitinib in ALS
It will be followed by a Q&A session.
The following experts in this disease will animate the discussion and answer questions.
- Dr Luis Barbeito
Institut Pasteur de Montevideo
- Dr Benjamin Brooks
Department of Neurology, Carolinas Medical Center
- Dr Conrado Estol
Buenos Aires, Argentina
- Pr Olivier Hermine
Division of Hematology/Oncology, Necker University Hospital
- Dr Jesus S. Mora
ALS Unit, Hospital Carlos III
The presentation supporting this conference call will be made available on AB science web site upon completion of the web call.
Masitinib is a new orally administered tyrosine kinase inhibitor that targets mast cells and macrophages, important cells for immunity, through inhibiting a limited number of kinases. Based on its unique mechanism of action, masitinib can be developed in a large number of conditions in oncology, in inflammatory diseases, and in certain diseases of the central nervous system. In oncology due to its immunotherapy effect, masitinib can have an effect on survival, alone or in combination with chemotherapy. Through its activity on mast cells and consequently the inhibition of the activation of the inflammatory process, masitinib can have an effect on the symptoms associated with some inflammatory and central nervous system diseases and the degeneration of these diseases.
About AB Science
Founded in 2001, AB Science is a pharmaceutical company specializing in the research, development and commercialization of protein kinase inhibitors (PKIs), a class of targeted proteins whose action are key in signaling pathways within cells. Our programs target only diseases with high unmet medical needs, often lethal with short term survival or rare or refractory to previous line of treatment in cancers, inflammatory diseases, and central nervous system diseases, both in human and animal health.
AB Science has developed a proprietary portfolio of molecules and the Company's lead compound, masitinib, has already been registered for veterinary medicine in Europe and in the USA. The company is currently pursuing thirteen phase 3 studies in human medicine in first-line and second-line GIST, metastatic melanoma expressing JM mutation of c-Kit, multiple myeloma, metastatic colorectal cancer, metastatic prostate cancer, pancreatic cancer, mastocytosis, severe persistent asthma, rheumatoid arthritis, Alzheimer's disease, progressive forms of multiple sclerosis, and Amyotrophic Lateral Sclerosis. The company is headquartered in Paris, France, and listed on Euronext Paris (ticker: AB).
Further information is available on AB Science's website: www.ab-science.com
This document contains prospective information. No guarantee can be given as for the realization of these forecasts, which are subject to those risks described in documents deposited by the Company to the Authority of the financial markets, including trends of the economic conjuncture, the financial markets and the markets on which AB Science is present.
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