"It's Shakespeare," Cramer said, referring to "Much Ado About Nothing."
Cramer made his remarks on "Squawk on the Street" after Re/code reported that the company has held talks to acquire Flipboard, a social network aggregation mobile app, for over $1 billion.
"If it helps them monetize, which some people say it would, that's fine. I know the whole problem with Twitter is that all the little things they do come up with don't move the needle," Cramer said.
""I think that [Twitter CFO] Anthony Noto is trying. I think that they're trying, [but] every time I talk to advertisers they say the same thing: 'We're not really getting our bang for our buck.'"
Twitter shares were flat Tuesday morning. Click here to see where the stock is trading now.
Disclosure: Cramer's trust owned Twitter stock when this article was published.
Disclaimer: CNBC's parent NBCUniversal is an investor in Re/code's parent Revere Digital, and the companies have a content-sharing arrangement.