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US stocks await GDP; Greece may weigh

U.S. stock markets looked set for a lower open on Friday, as uncertainty over Greece weighed on European shares and U.S. stock index futures.

The Greek government has said it hopes to reach a reform-for-rescue deal with its international bailout supervisors by Sunday, according to Reuters. However, European officials have denied a deal is near and Christine Lagarde, the head of the International Monetary Fund, was quoted in a German newspaper as saying that Greece talks could fail, forcing the country to default on its debts.

Read MoreGreek talks 'progressing'…so where's the deal?

The big data out of the U.S. on Friday will be the second estimate of first quarter gross domestic product (GDP), plus the Chicago Purchasing Managers' Index (PMI) and the final Michigan sentiment report for May.

The Commerce Department's first GDP estimate suggested the economy grew by an annualized 0.2 percent in the first three months of the year. However, more recent data suggests the economy may actually have contracted 1 percent during the first quarter.

Meanwhile, in stock news, the New York Post reported that Intel is close to a deal to buy smaller chipmaker Altera for around $15 billion.

No major earnings are due out on Friday from the U.S. In Canada, Bank of Nova Scotia will report.